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NCT06409663 · ClinicalTrials.gov registry record · Phase 3
A Strain Change Study for SARS-CoV-2 rS Vaccines
A Phase 3 study, sponsored by Novavax.
- Completed
- Registry status
- Phase 3
- Development phase
- 60
- Enrollment target
NCT06409663: Completed Phase 3 study, sponsored by Novavax.
NCT06409663 is a Phase 3 study that has completed, run by Novavax. The registered enrollment target is 60 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06409663, a Phase 3 study, has completed, sponsored by Novavax.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 60 participants
- Enrollment target
Study Summary
The present study aims to investigate the safety and immunogenicity of the Novavax JN.1 subvariant vaccine SARS-CoV-2 rS adjuvanted with Matrix-M (NVX CoV2705) in previously vaccinated adults. A descriptive comparison will be made with participants who received the prior authorized vaccine NVX-CoV2601 in an earlier study (2019nCoV-313).
Primary Outcome
Incidence, duration, and severity of solicited local and systemic adverse events (AEs) for 7 days following vaccination.
Interventions
- BIOLOGICAL NVX-CoV2705 Vaccine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-10-14 |
| Est. Completion | 2025-04-17 |
| Phase | Phase 3 |
What the finished NCT06409663 record still lists
NCT06409663 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which NVX-CoV2705 Vaccine is the first listed.
NCT06409663 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06409663 about?
NCT06409663 is a clinical study titled "A Strain Change Study for SARS-CoV-2 rS Vaccines". The present study aims to investigate the safety and immunogenicity of the Novavax JN.1 subvariant vaccine SARS-CoV-2 rS adjuvanted with Matrix-M (NVX CoV2705) in previously vaccinated adults. A descriptive comparison will be made with participants who received the prior authorized vaccine NVX-CoV26...
What is the current status of trial NCT06409663?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 60 participants. The study started on 2024-10-14. Estimated completion is 2025-04-17.
What interventions are being tested in trial NCT06409663?
The interventions under investigation include: NVX-CoV2705 Vaccine (BIOLOGICAL).
Who is sponsoring clinical trial NCT06409663?
This trial is sponsored by Novavax, which has 31 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06409663's enrollment target sits among peer trials
60 1804th of 2000 higher than 177 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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