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NCT00874393 · ClinicalTrials.gov registry record · Phase 1
Early Blood Pressure Management in Extremely Premature Infants
A Phase 1 study, sponsored by NICHD Neonatal Research Network.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT00874393: Completed Phase 1 study, sponsored by NICHD Neonatal Research Network.
NCT00874393 is a Phase 1 study that has completed, run by NICHD Neonatal Research Network. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00874393, a Phase 1 study, has completed, sponsored by NICHD Neonatal Research Network.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
This trial tests the feasibility of enrolling 60 extremely preterm infants in a randomized, double-blinded study of blood pressure management within 12 months. Eligible infants will receive an infusion drug (dopamine or a dextrose placebo) and a syringe drug (hydrocortisone or a normal saline placebo). Enrolled infants will be randomized to receive one of the following drug pairs: * dopamine and hydrocortisone * dopamine and normal saline * dextrose and hydrocortisone * dextrose and normal saline. In addition to the intervention above, the NRN is conducting a 6-month time-limited prospective observational study of all infants born at an NRN center between 23 and 26 weeks gestational age. All clinical decisions made for these babies will be at the discretion of the attending neonatologist/infant care team according to standard practice at each institution. Data on blood pressure management in the first 24 postnatal hours collected for each infant.
Interventions
- DRUG Dopamine
- DRUG Hydrocortisone
- DRUG Infusion Placebo
- DRUG Syringe Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2009-07 |
| Est. Completion | 2011-12 |
| Phase | Phase 1 |
What the finished NCT00874393 record still lists
NCT00874393 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 4 interventions - of which Dopamine is the first listed.
NCT00874393 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00874393 about?
NCT00874393 is a clinical study titled "Early Blood Pressure Management in Extremely Premature Infants". This trial tests the feasibility of enrolling 60 extremely preterm infants in a randomized, double-blinded study of blood pressure management within 12 months. Eligible infants will receive an infusion drug (dopamine or a dextrose placebo) and a syringe drug (hydrocortisone or a normal saline placeb...
What is the current status of trial NCT00874393?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2009-07. Estimated completion is 2011-12.
What interventions are being tested in trial NCT00874393?
The interventions under investigation include: Dopamine (DRUG), Hydrocortisone (DRUG), Infusion Placebo (DRUG), Syringe Placebo (DRUG).
Who is sponsoring clinical trial NCT00874393?
This trial is sponsored by NICHD Neonatal Research Network, which has 61 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00874393's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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