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NCT00233324 · ClinicalTrials.gov registry record · Phase 3

Surfactant Positive Airway Pressure and Pulse Oximetry Trial

A Phase 3 study, sponsored by NICHD Neonatal Research Network.

Completed
Registry status
Phase 3
Development phase
1,316
Enrollment target

NCT00233324 is a Phase 3 study that has completed, run by NICHD Neonatal Research Network. The registered enrollment target is 1,316 participants.

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The verdict

NCT00233324, a Phase 3 study, has completed, sponsored by NICHD Neonatal Research Network.

COMPLETED
Registry status
Phase 3
Development phase
1,316 participants
Enrollment target

Study Summary

This study compared the use of continuous positive airway pressure initiated at birth with the early administration of surfactant administered through a tube in the windpipe within 1 hour of birth for premature infants born at 24 to 27 weeks gestation. In addition, these infants within 2 hours of birth, had a special pulse oximeter placed to continuously monitor their oxygen saturation in two different target ranges (85-89% or 91-95%). This study helped determine whether or not these two management strategies affect chronic lung disease and survival of premature infants.

Interventions

  • DEVICE Continuous Positive Airway Pressure (CPAP)
  • DRUG Surfactant
  • DRUG Supplemental oxygen with target saturation of 85 to 89%
  • DRUG Supplemental oxygen with target saturation of 91 to 95%

Trial Details

FieldValue
Enrollment Target 1,316 participants
Start Date 2005-02
Est. Completion 2016-08
Phase Phase 3

Sponsor

NICHD Neonatal Research Network

61 total trials

What the Registry Record Tells You About NCT00233324

The ClinicalTrials.gov registry entry for NCT00233324 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 1,316 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NICHD Neonatal Research Network, which has 61 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Continuous Positive Airway Pressure (CPAP) is the first listed.

NCT00233324 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00233324 about?

NCT00233324 is a clinical study titled "Surfactant Positive Airway Pressure and Pulse Oximetry Trial". This study compared the use of continuous positive airway pressure initiated at birth with the early administration of surfactant administered through a tube in the windpipe within 1 hour of birth for premature infants born at 24 to 27 weeks gestation. In addition, these infants within 2 hours of bi...

What is the current status of trial NCT00233324?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,316 participants. The study started on 2005-02. Estimated completion is 2016-08.

What interventions are being tested in trial NCT00233324?

The interventions under investigation include: Continuous Positive Airway Pressure (CPAP) (DEVICE), Surfactant (DRUG), Supplemental oxygen with target saturation of 85 to 89% (DRUG), Supplemental oxygen with target saturation of 91 to 95% (DRUG).

Who is sponsoring clinical trial NCT00233324?

This trial is sponsored by NICHD Neonatal Research Network, which has 61 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.