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NCT00233324 · ClinicalTrials.gov registry record · Phase 3
Surfactant Positive Airway Pressure and Pulse Oximetry Trial
A Phase 3 study, sponsored by NICHD Neonatal Research Network.
- Completed
- Registry status
- Phase 3
- Development phase
- 1,316
- Enrollment target
NCT00233324: Completed Phase 3 study, sponsored by NICHD Neonatal Research Network.
NCT00233324 is a Phase 3 study that has completed, run by NICHD Neonatal Research Network. The registered enrollment target is 1,316 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (70% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00233324, a Phase 3 study, has completed, sponsored by NICHD Neonatal Research Network.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 1,316 participants
- Enrollment target
Study Summary
This study compared the use of continuous positive airway pressure initiated at birth with the early administration of surfactant administered through a tube in the windpipe within 1 hour of birth for premature infants born at 24 to 27 weeks gestation. In addition, these infants within 2 hours of birth, had a special pulse oximeter placed to continuously monitor their oxygen saturation in two different target ranges (85-89% or 91-95%). This study helped determine whether or not these two management strategies affect chronic lung disease and survival of premature infants.
Interventions
- DEVICE Continuous Positive Airway Pressure (CPAP)
- DRUG Surfactant
- DRUG Supplemental oxygen with target saturation of 85 to 89%
- DRUG Supplemental oxygen with target saturation of 91 to 95%
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,316 participants |
| Start Date | 2005-02 |
| Est. Completion | 2016-08 |
| Phase | Phase 3 |
What the finished NCT00233324 record still lists
NCT00233324 is an interventional study that assigns participants to a tested intervention. Its 1,316 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (70% higher).
The record links to 0 conditions, and to 4 interventions - of which Continuous Positive Airway Pressure (CPAP) is the first listed.
NCT00233324 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00233324 about?
NCT00233324 is a clinical study titled "Surfactant Positive Airway Pressure and Pulse Oximetry Trial". This study compared the use of continuous positive airway pressure initiated at birth with the early administration of surfactant administered through a tube in the windpipe within 1 hour of birth for premature infants born at 24 to 27 weeks gestation. In addition, these infants within 2 hours of bi...
What is the current status of trial NCT00233324?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,316 participants. The study started on 2005-02. Estimated completion is 2016-08.
What interventions are being tested in trial NCT00233324?
The interventions under investigation include: Continuous Positive Airway Pressure (CPAP) (DEVICE), Surfactant (DRUG), Supplemental oxygen with target saturation of 85 to 89% (DRUG), Supplemental oxygen with target saturation of 91 to 95% (DRUG).
Who is sponsoring clinical trial NCT00233324?
This trial is sponsored by NICHD Neonatal Research Network, which has 61 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00233324's enrollment target sits among peer trials
1,316 185th of 2000 higher than 1,816 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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