National Institute on Aging (NIA)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute on Aging (NIA) sits in the top decile of US sponsors by registered trial count (#209 of 15,742 sponsors by registered trial count).

131 total trials 12 currently recruiting 103 completed early-phase tilt top decile by trial count

National Institute on Aging (NIA): 131 sponsored US clinical trials, 12 recruiting.

National Institute on Aging (NIA) sponsors 131 registered US clinical trials on ClinicalTrials.gov, 12 of them currently recruiting, and 103 completed. 18 of these trials are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Aging, with 7 trials.

Top-decile sponsor footprint

National Institute on Aging (NIA) ranks in the top decile of sponsors by registered trial count (#209 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 62/100

103 of 116 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

131 total, page 3 of 3

COMPLETED

Osteoarthritis: Weakness From Inflammation

NCT00104312

COMPLETED Phase 4

PPV: Pneumococcal Polysaccharide Vaccine in Older Adults

NCT00239694

COMPLETED Phase 3

SeniorWISE: Improving Everyday Memory in At-Risk Elderly

NCT00094731

COMPLETED Phase 2

BVAIT: B-Vitamin Atherosclerosis Intervention Trial

NCT00114400

COMPLETED NA

PACT: Providers and Alzheimer's Caregivers Together

NCT00182897

COMPLETED Phase 4

Brain Imaging and Mental Disorders of Aging Intervention

NCT00267163

COMPLETED NA

Biological Effects of Dehydroepiandrosterone (DHEA) in the Elderly

NCT00111930

COMPLETED NA

Exercise for Elderly Peripheral Revascularized Patients

NCT00667290

COMPLETED NA

Alternative Therapies for Menopause: A Randomized Trial

NCT00061711

COMPLETED Phase 3

A Trial to Reduce Delirium in Aged Post Acute Patients

NCT00182936

COMPLETED NA

Obesity Prevention After Smoking Cessation in Menopause

NCT00064961

COMPLETED Phase 2

AFTER: Altering Fat Through Estrogen and Raloxifene

NCT00149604

COMPLETED NA

A Trial of Tap Water Treatment in the Elderly

NCT00058942

COMPLETED NA

Homeostatic Sleep Regulation in Older Persons

NCT00601445

COMPLETED Phase 1

Bryostatin 1 and Interleukin-2 in Treating Patients With Refractory Solid Tumors or Lymphoma

NCT00003993

COMPLETED Phase 2

The CHAT (Community Health Advice by Telephone) Study

NCT00131092

COMPLETED Phase 3

Memory Impairment Study (Mild Cognitive Impairment Study)

NCT00000173

COMPLETED

Metabolic Syndrome, Inflammation, and Risk of Cognitive Decline

NCT00099567

COMPLETED Phase 2

VEAPS: Vitamin E Atherosclerosis Prevention Study

NCT00114387

COMPLETED Phase 3

Estrogen Hormone Protocol

NCT00000177

COMPLETED Phase 2

EPAT: Estrogen in the Prevention of Atherosclerosis Trial

NCT00115024

COMPLETED NA

Exercise Rehabilitation of Younger and Older People With Claudication

NCT00654810

COMPLETED Phase 2

A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study)

NCT00004845

COMPLETED Phase 3

Multicenter Trial of Prednisone in Alzheimer's Disease

NCT00000178

COMPLETED Phase 3

Study of Melatonin: Sleep Problems in Alzheimer's Disease

NCT00000171

COMPLETED Phase 3

Alzheimer's Disease Prevention Trial

NCT00000176

COMPLETED Phase 1

AIT-082 Phase 1B Study

NCT00000180

COMPLETED Phase 3

Agitation in Alzheimer's Disease

NCT00000179

COMPLETED Phase 2

Effectiveness of A Nutritional Brain Metabolic Enhancer for Alzheimer Disease

NCT00013923

COMPLETED

Healthy Aging and Memory Study

NCT00034567

TERMINATED NA

The Effects of Sex Hormones on Cognition and Mood in Older Adults

NCT00000175

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Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 20
Phase 3 14
Phase 4 4

What is open in the National Institute on Aging (NIA) pipeline

12 recruiting of 131 indexed (9% open); 103 completed (79%).

Phase mix: 18 late (III/IV) vs 38 early (I/II) (early-phase heavy).

Top condition: Aging (7 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute on Aging (NIA): open-pipeline peers nationwide

Peers matched on 131 registered trials and 9% open enrollment, not the therapeutic-area sidebar.

National Institute on Aging (NIA) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150 5%10%15%20%25% Total trials Recruiting share National Institute on Aging (NIA)Rhode Island HospitalGeorge Washington UniversityUniversity of Illinois at Urbana-ChampaignJazz PharmaceuticalsAlkermesDBV TechnologiesFlorida Gulf Coast UniversityGenfit
National Institute on Aging (NIA) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute on Aging (NIA) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 131 trials (± recruiting share)

Sponsors near 9% open enrollment (± trial volume)

What to do with this National Institute on Aging (NIA) page

131 registered trials is a research-attention snapshot, not an endorsement of National Institute on Aging (NIA) or any single study.

  • 12 of National Institute on Aging (NIA)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Aging is the condition National Institute on Aging (NIA) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Aging trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institute on Aging (NIA) pipeline card: 131 registered trials from official public datasets.Report a data error.