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NCT00056225 · ClinicalTrials.gov registry record · Phase 3
VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study)
A Phase 3 study, sponsored by National Institute on Aging (NIA).
- Completed
- Registry status
- Phase 3
- Development phase
- 340
- Enrollment target
NCT00056225: Completed Phase 3 study, sponsored by National Institute on Aging (NIA).
NCT00056225 is a Phase 3 study that has completed, run by National Institute on Aging (NIA). The registered enrollment target is 340 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (56% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00056225, a Phase 3 study, has completed, sponsored by National Institute on Aging (NIA).
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 340 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether reduction of homocysteine levels with high-dose folate (folic acid), B6, and B12 supplementation will slow the rate of cognitive decline in persons with Alzheimer's disease.
Interventions
- DRUG Vitamin B12
- DRUG Folate
- DRUG Vitamin B6
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 340 participants |
| Start Date | 2003-01 |
| Est. Completion | 2007-06 |
| Phase | Phase 3 |
What the finished NCT00056225 record still lists
NCT00056225 is an interventional study that assigns participants to a tested intervention. The registered 340 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (56% lower).
The record links to 0 conditions, and to 3 interventions - of which Vitamin B12 is the first listed.
NCT00056225 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00056225 about?
NCT00056225 is a clinical study titled "VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study)". The purpose of this study is to determine whether reduction of homocysteine levels with high-dose folate (folic acid), B6, and B12 supplementation will slow the rate of cognitive decline in persons with Alzheimer's disease.
What is the current status of trial NCT00056225?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 340 participants. The study started on 2003-01. Estimated completion is 2007-06.
What interventions are being tested in trial NCT00056225?
The interventions under investigation include: Vitamin B12 (DRUG), Folate (DRUG), Vitamin B6 (DRUG).
Who is sponsoring clinical trial NCT00056225?
This trial is sponsored by National Institute on Aging (NIA), which has 131 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00056225's enrollment target sits among peer trials
340 1053rd of 2000 higher than 945 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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