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NCT00271154 · ClinicalTrials.gov registry record · NA

REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)

A NA study of Heart Failure, sponsored by Medtronic Cardiac Rhythm and Heart Failure.

Completed
Registry status
NA
Development phase
684
Enrollment target
20
Study locations

NCT00271154: Completed NA study of Heart Failure, sponsored by Medtronic Cardiac Rhythm and Heart Failure.

NCT00271154 is a NA study of Heart Failure that has completed, run by Medtronic Cardiac Rhythm and Heart Failure. The registered enrollment target is 684 participants, below the 2,047-participant average among 397 other Heart Failure trials with a reported enrollment target (67% lower). The trial reports 20 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00271154, a NA study of Heart Failure, has completed, sponsored by Medtronic Cardiac Rhythm and Heart Failure.

COMPLETED
Registry status
NA
Development phase
684 participants
Enrollment target
20
Study locations

Study Summary

Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes. When there are changes in the heart beat sometimes an implantable heart device is used to control the rate and rhythm of the heart beat. The purpose of the REVERSE clinical trial is to determine whether pacing in both the left and right ventricles using Cardiac Resynchronization Therapy (CRT) can help slow the progression of heart failure in people who have mild or previous symptoms and poor heart pumping function. This kind of therapy has previously been shown to reduce symptoms and improve exercise capacity in people with more advanced forms of heart failure.

Conditions Studied

Heart Failure

Interventions

  • DEVICE Cardiac Resynchronization Therapy (CRT) Device or Implantable Cardioverter Defibrillator (ICD) with CRT

Study Locations (20)

California

  • - Redwood City
  • - San Diego

Florida

  • - Atlantis
  • - Jacksonville

Massachusetts

  • - Boston
  • - Burlington

Michigan

  • - Ann Arbor
  • - Saginaw

New York

  • - East Syracuse
  • - Manhasset

Alabama

  • - Huntsville

Alaska

  • - Anchorage

Illinois

  • - Springfield

Trial Details

FieldValue
Enrollment Target 684 participants
Start Date 2004-09
Est. Completion 2011-11
Phase NA

Sponsor

Medtronic Cardiac Rhythm and Heart Failure

115 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00271154

The ClinicalTrials.gov registry entry for NCT00271154 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 684 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,047-participant average among 397 other Heart Failure trials with a reported enrollment target (67% lower). The listed sponsor is Medtronic Cardiac Rhythm and Heart Failure, which has 115 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which Cardiac Resynchronization Therapy (CRT) Device or Implantable Cardioverter Defibrillator (ICD) with CRT is the first listed.

NCT00271154 reports 20 study locations spanning 15 distinct geographic areas - top geographies include California, Florida, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00271154 about?

NCT00271154 is a clinical study titled "REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)". Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes. When there are changes in the heart beat sometimes an implantable heart device is used to control the rate and rhythm of the hear...

What is the current status of trial NCT00271154?

This trial is currently completed. It is a NA study. The enrollment target is 684 participants. The study started on 2004-09. Estimated completion is 2011-11.

What conditions does trial NCT00271154 study?

This clinical trial studies the following conditions: Heart Failure.

What interventions are being tested in trial NCT00271154?

The interventions under investigation include: Cardiac Resynchronization Therapy (CRT) Device or Implantable Cardioverter Defibrillator (ICD) with CRT (DEVICE).

Who is sponsoring clinical trial NCT00271154?

This trial is sponsored by Medtronic Cardiac Rhythm and Heart Failure, which has 115 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00271154 being conducted?

This trial has 20 study locations across Alabama, Alaska, California, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.