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NCT01458483 · ClinicalTrials.gov registry record · Phase 1
Acute Carotid Sinus Endovascular Stimulation II Study
A Phase 1 study, sponsored by Medtronic Cardiac Rhythm and Heart Failure.
- Completed
- Registry status
- Phase 1
- Development phase
- 9
- Enrollment target
NCT01458483: Completed Phase 1 study, sponsored by Medtronic Cardiac Rhythm and Heart Failure.
NCT01458483 is a Phase 1 study that has completed, run by Medtronic Cardiac Rhythm and Heart Failure. The registered enrollment target is 9 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01458483, a Phase 1 study, has completed, sponsored by Medtronic Cardiac Rhythm and Heart Failure.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
The Acute Carotid Sinus Endovascular Stimulation II (ACES II) Study is a multicenter, prospective, non-randomized study that is being conducted to evaluate the feasibility of endovascular stimulation of carotid sinus nerves via an electrophysiology (EP) catheter advanced into the internal jugular vein (IJV). The current study investigates the hypothesis that intraoperative electrical stimulation of the carotid sinus from the IJV will result in an acute and dose-dependent reduction in blood pressure and heart rate.
Interventions
- DEVICE Baroreceptor Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2011-10 |
| Est. Completion | 2012-10 |
| Phase | Phase 1 |
What the finished NCT01458483 record still lists
NCT01458483 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 1 intervention - of which Baroreceptor Stimulation is the first listed.
NCT01458483 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01458483 about?
NCT01458483 is a clinical study titled "Acute Carotid Sinus Endovascular Stimulation II Study". The Acute Carotid Sinus Endovascular Stimulation II (ACES II) Study is a multicenter, prospective, non-randomized study that is being conducted to evaluate the feasibility of endovascular stimulation of carotid sinus nerves via an electrophysiology (EP) catheter advanced into the internal jugular ve...
What is the current status of trial NCT01458483?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2011-10. Estimated completion is 2012-10.
What interventions are being tested in trial NCT01458483?
The interventions under investigation include: Baroreceptor Stimulation (DEVICE).
Who is sponsoring clinical trial NCT01458483?
This trial is sponsored by Medtronic Cardiac Rhythm and Heart Failure, which has 115 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01458483's enrollment target sits among peer trials
9 1955th of 2000 higher than 42 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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