Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 7 of 57

RECRUITING Phase 3

SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma

NCT06205316

RECRUITING NA

Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease

NCT06065436

RECRUITING Phase 1

ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Treatment of Recurrent High-Grade Glioma

NCT05917145

RECRUITING NA

Adipose Tissue Blood Flow in Aging Humans

NCT06096532

RECRUITING NA

Breathing Training and Exercise Capacity in Non-CFB

NCT05860803

RECRUITING

A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelae

NCT06006884

RECRUITING NA

Rapid Rehabilitation to Treat Lower Extremity Trauma

NCT05225792

RECRUITING NA

Acceptance and Commitment Therapy and Compassion-Based Virtual Group Therapy to Improve Psychological Wellbeing in Patients With Cancer

NCT06246955

RECRUITING Early Phase 1

MUSE-S Headband System for Improving Anxiety and Insomnia Among Breast Cancer Survivors

NCT06274034

RECRUITING Phase 1

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

NCT06508463

RECRUITING

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

NCT06151730

RECRUITING

Metabolic and Physiologic Responses to Hormone Therapy in Transgender and Gender Diverse People

NCT06083766

RECRUITING Phase 2

Alternate Doses and Dosing Schedules of Belantamab Mafodotin for Treatment of Triple-Class Refractory Multiple Myeloma

NCT05847569

RECRUITING NA

A Study of Pulmonary Hypertension Peripheral Limitations

NCT05968859

RECRUITING Early Phase 1

A Study of Niacin Regulation

NCT06175403

RECRUITING Early Phase 1

Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation

NCT06416969

RECRUITING Phase 2

Enfortumab Vedotin for the Treatment of Patients With Metastatic or Unresectable Squamous Cell Carcinoma of the Penis

NCT06104618

RECRUITING Phase 2

Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and Reconstruction

NCT06153836

RECRUITING NA

A Study to Evaluate Microvessel Ultrasound Imaging of Wound Healing in Patients With Chronic Ulcers

NCT05739149

RECRUITING Phase 1

Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis

NCT05802056

RECRUITING Phase 2

Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma

NCT06078709

RECRUITING

iCCaRE Consortium Pilot Project 1: Feasibility of a Point of Prostate Cancer Diagnosis Intervention for Newly Diagnosed Black Men

NCT06535802

RECRUITING NA

A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer

NCT06122064

RECRUITING NA

A Study of Breath Testing for Small Intestinal Bacterial Overgrowth

NCT05976165

RECRUITING NA

Accelerated Resolution Therapy for Early Maladaptive Grief

NCT05624879

RECRUITING

Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk

NCT06557057

RECRUITING

Disparities Among Liver Transplant Patients

NCT05981196

RECRUITING

A Study of Glycemic Control in Left Ventricular Assist

NCT05933161

RECRUITING NA

The Effect of Synaquell™ in Contact Sport Athletes

NCT06104670

RECRUITING

A Study to Determine Number of Patients Who Develop High Ammonia Levels After Receiving Recombinant Erwinia Asparaginase

NCT06600659

RECRUITING NA

Primary Breast Oligoprogressive Sites Treated With Radiotherapy to Obviate the Need to Change Systemic Therapy

NCT06055881

RECRUITING Phase 2

Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase Inhibitors

NCT06028022

RECRUITING NA

Using Facebook to Support Opioid Recovery Among American Indian Women

NCT05995886

RECRUITING

A Study of Invasive Hemodynamic for MACHD Registry

NCT05849025

RECRUITING NA

Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples

NCT06071845

RECRUITING

INTERogating Cancer for Etiology, Prevention and Therapy Navigation

NCT06008392

RECRUITING NA

Cardiac Rehabilitation Mobile-Health Fall Risk Prevention Intervention

NCT05826587

RECRUITING NA

The Use of Ultrasound in Assessing Post-prostatectomy Erectile Dysfunction

NCT05109208

RECRUITING Early Phase 1

Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma

NCT05717153

RECRUITING NA

Beetroot Juice and Sleep

NCT05864521

RECRUITING Phase 1

Vaccine Therapy Plus Pembrolizumab in Treating Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer

NCT05920798

RECRUITING

Exercise Response in Humans With Obesity

NCT05857150

RECRUITING NA

A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative Colitis

NCT05739162

RECRUITING

Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction

NCT05854303

RECRUITING NA

A Study of TopSpin360 Training Device

NCT06052553

RECRUITING Phase 2

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

NCT05969860

RECRUITING Phase 2

Daratumumab for Treatment of Proliferative Glomerulonephritis With Monoclonal Immune Deposits

NCT05654506

RECRUITING Phase 2

A Study of Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures

NCT05806996

RECRUITING Phase 3

NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis

NCT05992883

RECRUITING

Pulmonary Hypertension in Left Heart Disease

NCT05935605

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.