Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 6 of 57

RECRUITING NA

Techquity by FAITH!

NCT06187077

RECRUITING

The REgistry of Very Early Estrogen and AnovuLation

NCT06583408

RECRUITING

Molecular Analysis of Suspected or High-Risk Lung Cancer to Drive Individualized Care (Interception for Suspected Lung Cancer)

NCT06482073

RECRUITING Phase 2

Obinutuzumab in Treatment of Fibrillary Glomerulonephritis

NCT06295770

RECRUITING

Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary Tumors

NCT07335315

RECRUITING Phase 4

A Study of Contralateral Limb Block

NCT06045936

RECRUITING NA

Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer

NCT06389786

RECRUITING

Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids

NCT06106269

RECRUITING Phase 1

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma

NCT06058663

RECRUITING Phase 2

Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial

NCT06378866

RECRUITING Phase 2

Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

NCT06377696

RECRUITING NA

A Study of Virtual Reality and Linaclotide for IBS-C

NCT05796388

RECRUITING NA

A Pilot Study to Assess the Safety, Tolerability, and Efficacy of Virtual Reality for the Treatment of Abdominal Pain in Quiescent Crohn's Disease

NCT06647615

RECRUITING Phase 2

Reduced Dose Radiotherapy for the Treatment of Indolent Non-Hodgkin Lymphoma

NCT06386315

RECRUITING Phase 2

MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial

NCT06319248

RECRUITING NA

Whole Food Plant-based Diet Effect on Obstructive Sleep Apnea

NCT06395181

RECRUITING NA

Establishing Pressures at the EGJ During Diaphragmatic Breathing Using High-resolution Esophageal Manometry

NCT06329583

RECRUITING NA

Improving Outcomes in PICS With Home-Based Program of Rehabilitation and Health Coaching

NCT06184308

RECRUITING NA

Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black Men

NCT06541210

RECRUITING Phase 2

Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

NCT06200103

RECRUITING Early Phase 1

Regional Lipolysis Insulin Regulation

NCT06392854

RECRUITING NA

Continuous Glucose Monitor for Mayo Clinic Advanced Care at Home Patients

NCT05880810

RECRUITING Phase 2

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

NCT06265285

RECRUITING

DiviTum®TKa: A Biomarker Assay for Efficacy in HR+ Metastatic Breast Cancer Patients

NCT06388122

RECRUITING

Patient and Caregiver Priorities in Neuro-oncology Care

NCT06676306

RECRUITING

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

NCT06349642

RECRUITING Phase 2

Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment of Prostate Cancer

NCT06369610

RECRUITING

The Weight of Cardiovascular Disease

NCT06053645

RECRUITING

A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's Disease

NCT06057909

RECRUITING

A Study of AI in Cardiac Transplant in Echocardiographic Analysis (ORACLE)

NCT06178744

RECRUITING Phase 3

A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)

NCT06150560

RECRUITING NA

Functional Dyspepsia Treatment Using Virtual Reality

NCT05836597

RECRUITING

Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia With an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients With Post-Menopausal Bleeding

NCT06365905

RECRUITING

Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias

NCT06306963

RECRUITING Phase 4

Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications

NCT06401642

RECRUITING Phase 1

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

NCT06191887

RECRUITING

Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma

NCT06409013

RECRUITING NA

Fasting Mimicking Diet for Reducing Immune Related Adverse Events for Cancer Patients on Immune Checkpoint Inhibitors, FMD-ICI Trial

NCT06438588

RECRUITING NA

The TELENEO Trial: A Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals

NCT06087224

RECRUITING

A Study of Mayo Clinic CV Research Heart & Voice Study

NCT07224685

RECRUITING Phase 1

MC210808 Venetoclax in Combination With Lenalidomide and Dexamethasone (Ven-Rd), Daratumumab and Dexamethasone (Ven-Dd), or Daratumumab-Lenalidomide-Dexamethasone (Ven-DRd) for the Treatment of Multiple Myeloma

NCT06042725

RECRUITING

Study of Human Brain-Gut Axis and Gut Microbiome in Patients With Brain Lesions - Repository for Neuroscience Research

NCT06117930

RECRUITING NA

Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

NCT06322602

RECRUITING NA

A Study of Healthy Microbiome, Healthy Mind

NCT06020703

RECRUITING NA

Breast Cancer, Reasoning, and Activity Intervention

NCT04816006

RECRUITING Phase 2

Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis

NCT04858009

RECRUITING NA

Virtual Reality for Non-cardiac Chest Pain

NCT06262126

RECRUITING Phase 4

Low Sodium Oxybate in Patients With Idiopathic Hypersomnia

NCT05837091

RECRUITING NA

A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors (ASCENT)

NCT06198010

RECRUITING NA

Extracellular Impact of Ultrasound-induced Blood-brain Barrier Disruption

NCT05733312

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.