Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01240252 · ClinicalTrials.gov registry record · Phase 1

Insulin Receptor Substrate 1 (IRS-1) Regulation in Insulin Resistance

A Phase 1 study, sponsored by Mayo Clinic.

Completed
Registry status
Phase 1
Development phase
14
Enrollment target

NCT01240252: Completed Phase 1 study, sponsored by Mayo Clinic.

NCT01240252 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 14 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT01240252, a Phase 1 study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 1
Development phase
14 participants
Enrollment target

Study Summary

The study is being conducted to find out why too much fat in your blood stream may cause insulin resistance in your muscles. Insulin is the hormone, produced normally by your body, which causes your blood sugar to return to normal after you eat.

Primary Outcome

IRS-1 will be immunoprecipitated from percutaneous muscle biopsies, resolved by gel electrophoresis, digested with trypsin, and analyzed by high-performance liquid chromatography nanospray tandem mass spectrometry (MS/MS) analysis

Interventions

  • DRUG Human insulin

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2012-03
Est. Completion 2012-07
Phase Phase 1
Mayo Clinic

2,844 total trials

What the finished NCT01240252 record still lists

NCT01240252 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 1 intervention - of which Human insulin is the first listed.

NCT01240252 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01240252 about?

NCT01240252 is a clinical study titled "Insulin Receptor Substrate 1 (IRS-1) Regulation in Insulin Resistance". The study is being conducted to find out why too much fat in your blood stream may cause insulin resistance in your muscles. Insulin is the hormone, produced normally by your body, which causes your blood sugar to return to normal after you eat.

What is the current status of trial NCT01240252?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2012-03. Estimated completion is 2012-07.

What interventions are being tested in trial NCT01240252?

The interventions under investigation include: Human insulin (DRUG).

Who is sponsoring clinical trial NCT01240252?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01240252's enrollment target sits among peer trials

14 1844th of 2000 higher than 154 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02523092 · 14 participants · Phase 4

    Use of CXCL9 as a Biomarker of Acthar Efficacy

  • NCT04263285 · 14 participants · NA

    Treatment of Depression Post-SCI

  • NCT04743271 · 14 participants · NA

    Food and Circadian Timing

  • NCT05065671 · 14 participants · Phase 1

    Microbiome Derived Metabolism and Pharmacokinetics

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01240252, the US trial registry maintained by the National Library of Medicine. NCT01240252 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.