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NCT03718494 · ClinicalTrials.gov registry record
Continuation of The Kronos Early Estrogen Prevention Study (KEEPS)
A clinical trial, sponsored by Mayo Clinic.
- Completed
- Registry status
- 299
- Enrollment target
NCT03718494: Completed study, sponsored by Mayo Clinic.
NCT03718494 is a clinical trial that has completed, run by Mayo Clinic. The registered enrollment target is 299 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03718494 has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- 299 participants
- Enrollment target
Study Summary
The purpose of this study is to investigate how blood flow to the brain affects cognition in women who are postmenopausal, and how the use of hormone therapy early in menopause might change brain function. The testing in this study will add to the knowledge about brain aging in women. Researchers will determine if blood flow to the brain, brain structure, and cognition differences among women who took hormones in the past as part of Kronos Early Estrogen Prevention Study (KEEPS; NCT00154180), are currently taking hormones, or never took menopausal hormones.
Primary Outcome
This measure is derived from a PET imaging study that images the deposition of the amyloid plaques of Alzheimer's disease in the brain
Interventions
- DIAGNOSTIC_TEST Brain Magnetic Resonance Imaging (MRI)
- OTHER Neuropsychological Testing
- DIAGNOSTIC_TEST F-18 Florbetapir Positron Emission Tomography (PET) Imaging
- DIAGNOSTIC_TEST F-18 AV-1451 Positron Emission Tomography (PET) Imaging
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 299 participants |
| Start Date | 2019-05-22 |
| Est. Completion | 2022-09-01 |
What the finished NCT03718494 record still lists
NCT03718494 is an observational study that tracks outcomes without assigning an intervention. The registered 299 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 4 interventions - of which Brain Magnetic Resonance Imaging (MRI) is the first listed.
NCT03718494 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03718494 about?
NCT03718494 is a clinical study titled "Continuation of The Kronos Early Estrogen Prevention Study (KEEPS)". The purpose of this study is to investigate how blood flow to the brain affects cognition in women who are postmenopausal, and how the use of hormone therapy early in menopause might change brain function. The testing in this study will add to the knowledge about brain aging in women. Researchers wi...
What is the current status of trial NCT03718494?
This trial is currently completed. The enrollment target is 299 participants. The study started on 2019-05-22. Estimated completion is 2022-09-01.
What interventions are being tested in trial NCT03718494?
The interventions under investigation include: Brain Magnetic Resonance Imaging (MRI) (DIAGNOSTIC_TEST), Neuropsychological Testing (OTHER), F-18 Florbetapir Positron Emission Tomography (PET) Imaging (DIAGNOSTIC_TEST), F-18 AV-1451 Positron Emission Tomography (PET) Imaging (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03718494?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
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