Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 7 of 41
Developing Viability Index for Machine Perfused Livers
NCT03694691
Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy
NCT03286335
Imaging Histone Deacetylase in the Heart
NCT03549559
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
NCT04496947
Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis Patients
NCT03535545
Durvalumab (MEDI4736) and Tremelimumab and Radiation Therapy in Hepatocellular Carcinoma and Biliary Tract Cancer
NCT03482102
BezafibrateTreatment for Bipolar Depression: A Proof of Concept Study
NCT02481245
Pilot Study for OCT Guided In Vivo Laser Capture Microdissection for Assessing the Prognosis of Barrett's Esophagus
NCT03830801
Biomarker Profiling in Individuals at Risk for Prion Disease
NCT05124392
Turmeric for Patients With Basal Joint Arthritis
NCT03017118
Diffusion MRI in Heart Failure
NCT02973633
Stroke Motor Rehabilitation and Recovery Study
NCT03485040
Palbociclib and Pembrolizumab In Central Nervous System Metastases
NCT02896335
Partners Calciphylaxis Biobank
NCT03032835
Caloric Restriction In Sarcoma Patients Treated With Pre-Operative RT
NCT02792270
Pilot Study for TCE Imaging of the Esophagus Using an OFDI Capsule With a Compact Imaging System
NCT02947971
Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure
NCT03480633
Positron Emission Tomography (PET) Imaging of Thrombosis
NCT03830320
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
NCT07022951
ALS/MND Natural History Study Data Repository
NCT05966038
Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer
NCT02290834
Biomarker Development for Muscular Dystrophies
NCT05019625
Bronchial NIR Image-guided Resection
NCT03097575
Adhesive Capsulitis: Prospective Analysis of Efficacy and Financial Impact for Use of Physical Therapy in Treatment
NCT02283996
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
NCT04296604
Phase II Study of Proton Radiation Therapy for Neuroblastoma
NCT02112617
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study
NCT02061306
A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia
NCT02118922
Proton or Photon RT for Retroperitoneal Sarcomas
NCT01659203
Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy
NCT01696721
A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in Newborn
NCT01873131
Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy
NCT01961713
Prospective Screening for Breast Cancer-related Lymphedema
NCT01521741
National Pregnancy Registry for Psychiatric Medications
NCT01246765
DNA Analysis of Blood and Tissue from Patients with Lung Cancer
NCT00471978
Molecular and Genetic Analysis of Lung Cancer
NCT03029325
Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair
NCT07498166
Trial of Oral Digoxin in Individuals With Amyotrophic Lateral Sclerosis (ALS)
NCT07047209
Resilient Families Open Pilot: Dyadic Resiliency Intervention
NCT06239571
Open Pilot Trial of a Mind-Body Intervention for Patients With Chronic Hip Pain
NCT06820242
Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression
NCT05774665
Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome
NCT06698848
Vedolizumab for the Treatment of Collagenous Gastritis
NCT06317220
Sequential Multiple Assignment Randomized Trial for Bipolar Depression
NCT06433635
Tele-Palliative Care Intervention for Patients With Chronic Graft-Versus-Host Disease
NCT06458127
CHW Intervention to Improve Nutrition Security of Patients With Hypertension
NCT06358417
Promoting Stress Management and Resilience Among Individuals With Von Hippel- Lindau Disease
NCT05737602
REACH-Es: Adapting a Digital Health Tool to Improve Diabetes Medication Adherence Among Latino Adults
NCT06000813
Preventing Disordered Eating and Body Dissatisfaction Among High-risk Pregnant Individuals
NCT06659354
Pomalidomide for the Treatment of Bleeding in Hereditary Hemorrhagic Telangiectasia Longitudinal Assessment Study
NCT07018401
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.