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NCT00592748 · ClinicalTrials.gov registry record · Phase 1
Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine
A Phase 1 study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Phase 1
- Development phase
- 381
- Enrollment target
NCT00592748: Completed Phase 1 study, sponsored by Massachusetts General Hospital.
NCT00592748 is a Phase 1 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 381 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (535% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00592748, a Phase 1 study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 381 participants
- Enrollment target
Study Summary
The primary purpose of this study is to determine if the administration of a higher dose would decrease the chance of tumor recurrence, compared to the risk of tumor recurrence with a lower dose. Most of the treatment will be given protons, but participants may receive a small portion of treatment with x-rays, because less radiation is given to the skin with x-rays. This study uses two slightly different doses of radiation It is not clear at this time which of the dose levels is better.
Interventions
- RADIATION Charged Particle Radiation Therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 381 participants |
| Start Date | 1999-06 |
| Est. Completion | 2015-05 |
| Phase | Phase 1 |
What the finished NCT00592748 record still lists
NCT00592748 is an interventional study that assigns participants to a tested intervention. The registered 381 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (535% higher).
The record links to 0 conditions, and to 1 intervention - of which Charged Particle Radiation Therapy is the first listed.
NCT00592748 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00592748 about?
NCT00592748 is a clinical study titled "Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine". The primary purpose of this study is to determine if the administration of a higher dose would decrease the chance of tumor recurrence, compared to the risk of tumor recurrence with a lower dose. Most of the treatment will be given protons, but participants may receive a small portion of treatment w...
What is the current status of trial NCT00592748?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 381 participants. The study started on 1999-06. Estimated completion is 2015-05.
What interventions are being tested in trial NCT00592748?
The interventions under investigation include: Charged Particle Radiation Therapy (RADIATION).
Who is sponsoring clinical trial NCT00592748?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00592748's enrollment target sits among peer trials
381 81st of 2000 higher than 1,920 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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