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NCT00118417 · ClinicalTrials.gov registry record · Phase 2

Therapies for Treatment-Resistant Panic Disorder Symptoms

A Phase 2 study, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 2
Development phase
46
Enrollment target

NCT00118417: Completed Phase 2 study, sponsored by Massachusetts General Hospital.

NCT00118417 is a Phase 2 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 46 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00118417, a Phase 2 study, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 2
Development phase
46 participants
Enrollment target

Study Summary

This study will determine the effectiveness of different treatments for panic disorder symptoms in individuals who still have symptoms after initial treatment with medication.

Primary Outcome

This measure is the change in points between baseline and endpoint scores on the Panic Disorder Severity Scale (PDSS). The PDSS is a 7-item scale with each item rated from 0 (none) to 4 (extreme), for a total score range of 0 to 28 points, and an established interrater reliability of 0.87.

Interventions

  • DRUG Sertraline
  • DRUG Clonazepam
  • BEHAVIORAL Cognitive behavioral therapy

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 1999-03
Est. Completion 2007-10
Phase Phase 2
Massachusetts General Hospital

2,032 total trials

What the finished NCT00118417 record still lists

NCT00118417 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (65% lower).

The record links to 0 conditions, and to 3 interventions - of which Sertraline is the first listed.

NCT00118417 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00118417 about?

NCT00118417 is a clinical study titled "Therapies for Treatment-Resistant Panic Disorder Symptoms". This study will determine the effectiveness of different treatments for panic disorder symptoms in individuals who still have symptoms after initial treatment with medication.

What is the current status of trial NCT00118417?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 46 participants. The study started on 1999-03. Estimated completion is 2007-10.

What interventions are being tested in trial NCT00118417?

The interventions under investigation include: Sertraline (DRUG), Clonazepam (DRUG), Cognitive behavioral therapy (BEHAVIORAL).

Who is sponsoring clinical trial NCT00118417?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00118417's enrollment target sits among peer trials

46 1286th of 2000 higher than 705 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00118417, the US trial registry maintained by the National Library of Medicine. NCT00118417 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.