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NCT01525446 · ClinicalTrials.gov registry record · Early Phase 1
Proton Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer
A Early Phase 1 study, sponsored by Massachusetts General Hospital.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 7
- Enrollment target
NCT01525446: Clinical Trial Early Phase 1 study, sponsored by Massachusetts General Hospital.
NCT01525446 is a Early Phase 1 study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 7 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01525446, a Early Phase 1 study, was terminated before completion, sponsored by Massachusetts General Hospital.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
Stereotactic body radiation therapy (SBRT) is a special form of treatment which pinpoints high doses of radiation directly to cancer. Standard radiation (or photon radiation) is commonly used for SBRT to treat Non-Small Cell Lung Cancer (NSCLC). Proton beam radiation is a special type of radiation only available at a few institutions in the US and has not been previously used in SBRT to treat NSCLC. The use of protons for SBRT may improve the accuracy of the treatment and may help to minimize the dose delivered unnecessarily to healthy tissue. In this study, the investigators are evaluating the safety and effectiveness of proton-based SBRT for early-stage NSCLC located in the periphery of the lung.
Primary Outcome
To establish the feasibility and safety of fiducials placement by electromagnetic navigational bronchoscopy (ENB)
Interventions
- RADIATION SBRT with proton beam radiation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2011-09 |
| Est. Completion | 2015-12 |
| Phase | Early Phase 1 |
Why NCT01525446 stopped before completion
NCT01525446 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 1 intervention - of which SBRT with proton beam radiation is the first listed.
NCT01525446 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01525446 about?
NCT01525446 is a clinical study titled "Proton Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer". Stereotactic body radiation therapy (SBRT) is a special form of treatment which pinpoints high doses of radiation directly to cancer. Standard radiation (or photon radiation) is commonly used for SBRT to treat Non-Small Cell Lung Cancer (NSCLC). Proton beam radiation is a special type of radiation o...
What is the current status of trial NCT01525446?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 7 participants. The study started on 2011-09. Estimated completion is 2015-12.
What interventions are being tested in trial NCT01525446?
The interventions under investigation include: SBRT with proton beam radiation (RADIATION).
Who is sponsoring clinical trial NCT01525446?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01525446's enrollment target sits among peer trials
7 1825th of 2000 higher than 156 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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