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NCT03292159 · ClinicalTrials.gov registry record · Phase 1
Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke
A Phase 1 study, sponsored by Massachusetts General Hospital.
- Terminated
- Registry status
- Phase 1
- Development phase
- 6
- Enrollment target
NCT03292159: Clinical Trial Phase 1 study, sponsored by Massachusetts General Hospital.
NCT03292159 is a Phase 1 study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03292159, a Phase 1 study, was terminated before completion, sponsored by Massachusetts General Hospital.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 6 participants
- Enrollment target
Study Summary
This study will evaluate the safety and effectiveness of Respiratory-gated Auricular Vagal Afferent Nerve Stimulation (RAVANS) for improving motor recovery after stroke. Subacute stroke patients will receive RAVANS or sham stimulation concurrent with arm motor training during 10 intervention sessions occurring daily for 30 minutes over 2 weeks. The safety and improvements in arm motor function after the intervention will be compared in patients receiving RAVANS to those receiving sham stimulation.
Primary Outcome
Change in upper extremity subtest of Fugl Meyer Assessment (FMA-UE) score
Interventions
- DEVICE Active RAVANS concurrent with arm motor training
- DEVICE Inactive RAVANS concurrent with arm motor training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2018-05-17 |
| Est. Completion | 2018-11-20 |
| Phase | Phase 1 |
Why NCT03292159 stopped before completion
NCT03292159 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Active RAVANS concurrent with arm motor training is the first listed.
NCT03292159 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03292159 about?
NCT03292159 is a clinical study titled "Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke". This study will evaluate the safety and effectiveness of Respiratory-gated Auricular Vagal Afferent Nerve Stimulation (RAVANS) for improving motor recovery after stroke. Subacute stroke patients will receive RAVANS or sham stimulation concurrent with arm motor training during 10 intervention session...
What is the current status of trial NCT03292159?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2018-05-17. Estimated completion is 2018-11-20.
What interventions are being tested in trial NCT03292159?
The interventions under investigation include: Active RAVANS concurrent with arm motor training (DEVICE), Inactive RAVANS concurrent with arm motor training (DEVICE).
Who is sponsoring clinical trial NCT03292159?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03292159's enrollment target sits among peer trials
6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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