Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00097448 · ClinicalTrials.gov registry record · Phase 3
Sudden Deafness Treatment Trial
A Phase 3 study, sponsored by Massachusetts Eye and Ear Infirmary.
- Completed
- Registry status
- Phase 3
- Development phase
- 255
- Enrollment target
NCT00097448: Completed Phase 3 study, sponsored by Massachusetts Eye and Ear Infirmary.
NCT00097448 is a Phase 3 study that has completed, run by Massachusetts Eye and Ear Infirmary. The registered enrollment target is 255 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00097448, a Phase 3 study, has completed, sponsored by Massachusetts Eye and Ear Infirmary.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 255 participants
- Enrollment target
Study Summary
This trial aims to compare the efficacy of oral prednisone vs. methylprednisolone injected into the middle ear for the treatment of moderate-to-severe, sudden sensorineural hearing loss (inner ear hearing loss affecting one ear that occurs over less than 72 hours).
Primary Outcome
Change from baseline to 2mos of 4-frequency (500, 1000, 2000, 4000Hz) pure tone average.
Interventions
- DRUG prednisone
- DRUG methylprednisolone sodium succinate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 255 participants |
| Start Date | 2004-12 |
| Est. Completion | 2011-03 |
| Phase | Phase 3 |
What the finished NCT00097448 record still lists
NCT00097448 is an interventional study that assigns participants to a tested intervention. The registered 255 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 2 interventions - of which prednisone is the first listed.
NCT00097448 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00097448 about?
NCT00097448 is a clinical study titled "Sudden Deafness Treatment Trial". This trial aims to compare the efficacy of oral prednisone vs. methylprednisolone injected into the middle ear for the treatment of moderate-to-severe, sudden sensorineural hearing loss (inner ear hearing loss affecting one ear that occurs over less than 72 hours).
What is the current status of trial NCT00097448?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 255 participants. The study started on 2004-12. Estimated completion is 2011-03.
What interventions are being tested in trial NCT00097448?
The interventions under investigation include: prednisone (DRUG), methylprednisolone sodium succinate (DRUG).
Who is sponsoring clinical trial NCT00097448?
This trial is sponsored by Massachusetts Eye and Ear Infirmary, which has 73 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00097448's enrollment target sits among peer trials
255 1242nd of 2000 higher than 756 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04623424 · 255 participants
Intestinal Microbiota in Stem Cell Transplant Transplant Admission
- NCT05114798 · 255 participants · NA
Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers
- NCT05336188 · 255 participants · Phase 2
Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder
- NCT05486637 · 255 participants · Early Phase 1
Vocal Emotion Communication With Cochlear Implants
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia