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NCT00553735 · ClinicalTrials.gov registry record · Phase 4
The Prophylactic Use of Topical Cyclosporine A 0.05% to Prevent Graft Versus Host Disease Related Dry Eye
A Phase 4 study, sponsored by Massachusetts Eye and Ear Infirmary.
- Terminated
- Registry status
- Phase 4
- Development phase
- 8
- Enrollment target
NCT00553735: Clinical Trial Phase 4 study, sponsored by Massachusetts Eye and Ear Infirmary.
NCT00553735 is a Phase 4 study that was terminated before completion, run by Massachusetts Eye and Ear Infirmary. The registered enrollment target is 8 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00553735, a Phase 4 study, was terminated before completion, sponsored by Massachusetts Eye and Ear Infirmary.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 8 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether Restasis is an effective treatment for preventing the occurrence and progression of dry eye syndrome in patients who have recently received a bone marrow transplant and are at risk to graft-versus-host disease.
Interventions
- DRUG Cyclosporine A 0.05%
- DRUG Arificial Tear
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2007-08 |
| Est. Completion | 2010-12 |
| Phase | Phase 4 |
Why NCT00553735 stopped before completion
NCT00553735 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Cyclosporine A 0.05% is the first listed.
NCT00553735 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00553735 about?
NCT00553735 is a clinical study titled "The Prophylactic Use of Topical Cyclosporine A 0.05% to Prevent Graft Versus Host Disease Related Dry Eye". The purpose of this study is to determine whether Restasis is an effective treatment for preventing the occurrence and progression of dry eye syndrome in patients who have recently received a bone marrow transplant and are at risk to graft-versus-host disease.
What is the current status of trial NCT00553735?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 8 participants. The study started on 2007-08. Estimated completion is 2010-12.
What interventions are being tested in trial NCT00553735?
The interventions under investigation include: Cyclosporine A 0.05% (DRUG), Arificial Tear (DRUG).
Who is sponsoring clinical trial NCT00553735?
This trial is sponsored by Massachusetts Eye and Ear Infirmary, which has 73 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00553735's enrollment target sits among peer trials
8 1972nd of 2000 higher than 20 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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