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NCT00559936 · ClinicalTrials.gov registry record · Phase 1

Topical Avastin for Treatment of Corneal Neovascularization

A Phase 1 study, sponsored by Massachusetts Eye and Ear Infirmary.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target

NCT00559936: Completed Phase 1 study, sponsored by Massachusetts Eye and Ear Infirmary.

NCT00559936 is a Phase 1 study that has completed, run by Massachusetts Eye and Ear Infirmary. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00559936, a Phase 1 study, has completed, sponsored by Massachusetts Eye and Ear Infirmary.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target

Study Summary

The purpose of this study is to determine the effectiveness and safety of Topical Bevacizumab (Avastin) for treatment of corneal neovascularization.

Primary Outcome

The efficacy of bevacizumab in the treatment of corneal NV was evaluated by comparing corneal photographs taken at baseline with corneal photographs taken at the follow-up visits. Percent change from baseline was measured.

Interventions

  • DRUG Topical Avastin 1%

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2007-02
Est. Completion 2010-10
Phase Phase 1

What the finished NCT00559936 record still lists

NCT00559936 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).

The record links to 0 conditions, and to 1 intervention - of which Topical Avastin 1% is the first listed.

NCT00559936 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00559936 about?

NCT00559936 is a clinical study titled "Topical Avastin for Treatment of Corneal Neovascularization". The purpose of this study is to determine the effectiveness and safety of Topical Bevacizumab (Avastin) for treatment of corneal neovascularization.

What is the current status of trial NCT00559936?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2007-02. Estimated completion is 2010-10.

What interventions are being tested in trial NCT00559936?

The interventions under investigation include: Topical Avastin 1% (DRUG).

Who is sponsoring clinical trial NCT00559936?

This trial is sponsored by Massachusetts Eye and Ear Infirmary, which has 73 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00559936's enrollment target sits among peer trials

24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00559936, the US trial registry maintained by the National Library of Medicine. NCT00559936 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.