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NCT01364207 · ClinicalTrials.gov registry record · NA
The Effects of Caffeinated Coffee on Intraocular Pressure
A NA study, sponsored by Massachusetts Eye and Ear Infirmary.
- Completed
- Registry status
- NA
- Development phase
- 112
- Enrollment target
NCT01364207: Completed NA study, sponsored by Massachusetts Eye and Ear Infirmary.
NCT01364207 is a NA study that has completed, run by Massachusetts Eye and Ear Infirmary. The registered enrollment target is 112 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01364207, a NA study, has completed, sponsored by Massachusetts Eye and Ear Infirmary.
- COMPLETED
- Registry status
- NA
- Development phase
- 112 participants
- Enrollment target
Study Summary
High intraocular pressure (IOP) is a known risk factor for developing primary open-angle glaucoma (POAG). There is controversy in the literature regarding the degree to which caffeine influences IOP, with some studies reporting minimal changes in IOP while others report up to 4 mmHg increases. To date there are no double-masked randomized controlled trials that examine acute caffeinated coffee's effects on IOP in patients with or at risk for primary open-angle glaucoma. The investigators aim to better understand the relationship between acute caffeinated coffee (vs decaffeinate coffee) consumption and IOP in a double-masked, crossover randomized controlled clinical trial.
Primary Outcome
At the caffeinated coffee visit: Change in intraocular pressure at 60 minutes = intraocular pressure at 60 minutes post caffeinated coffee ingestion minus intraocular pressure at baseline prior to caffeinated coffee ingestion At the decaffeinated coffee visit: Change in intraocular pressure at 60 minutes = intraocular pressure at 60 minutes post decaffeinated coffee ingestion minus intraocular pressure at baseline prior to decaffeinated coffee ingestion
Interventions
- OTHER Caffeinated Coffee
- OTHER Decaffeinated Coffee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 112 participants |
| Start Date | 2010-11 |
| Est. Completion | 2012-06 |
| Phase | NA |
What the finished NCT01364207 record still lists
NCT01364207 is an interventional study that assigns participants to a tested intervention. The registered 112 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 2 interventions - of which Caffeinated Coffee is the first listed.
NCT01364207 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01364207 about?
NCT01364207 is a clinical study titled "The Effects of Caffeinated Coffee on Intraocular Pressure". High intraocular pressure (IOP) is a known risk factor for developing primary open-angle glaucoma (POAG). There is controversy in the literature regarding the degree to which caffeine influences IOP, with some studies reporting minimal changes in IOP while others report up to 4 mmHg increases. To da...
What is the current status of trial NCT01364207?
This trial is currently completed. It is a NA study. The enrollment target is 112 participants. The study started on 2010-11. Estimated completion is 2012-06.
What interventions are being tested in trial NCT01364207?
The interventions under investigation include: Caffeinated Coffee (OTHER), Decaffeinated Coffee (OTHER).
Who is sponsoring clinical trial NCT01364207?
This trial is sponsored by Massachusetts Eye and Ear Infirmary, which has 73 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01364207's enrollment target sits among peer trials
112 813th of 2000 higher than 1,185 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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