Janssen Research & Development

593 total trials 68 currently recruiting 384 completed

Janssen Research & Development sponsors 593 registered US clinical trials on ClinicalTrials.gov, 68 of them currently recruiting, and 384 completed. 179 of these trials are in Phase 3-4 (later-stage) and 377 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 25 trials.

Trial Pipeline

593 total, page 4 of 12

ACTIVE NOT RECRUITING Phase 1

Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

NCT03399799

ACTIVE NOT RECRUITING Phase 3

A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma

NCT03301220

ACTIVE NOT RECRUITING Phase 1

Dose Escalation Study of Teclistamab, a Humanized BCMA*CD3 Bispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma

NCT03145181

ACTIVE NOT RECRUITING Phase 1

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Participants With Advanced Cancers

NCT02908906

ACTIVE NOT RECRUITING Phase 1

Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer

NCT02609776

ACTIVE NOT RECRUITING Phase 2

An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

NCT02365597

NOT YET RECRUITING Phase 4

A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

NCT07654751

TERMINATED Phase 3

A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

NCT06635135

TERMINATED Phase 3

A Study of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy and Long-term Extension Treatment With Aticaprant

NCT06514742

COMPLETED Early Phase 1

A Study of Sterile Saline Infusion in Healthy Volunteers

NCT06194578

COMPLETED Phase 3

A Study of 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) and High-dose Quadrivalent Influenza Vaccine, With and Without Co-administration, in Adults Aged 65 Years or Older

NCT06134804

COMPLETED Phase 2

A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis

NCT06049017

COMPLETED Phase 3

Study of Guselkumab Versus Placebo for the Treatment of Low Body Surface Area Moderate Plaque Psoriasis

NCT06039189

COMPLETED Phase 2

A Study to Evaluate the Nipocalimab and Certolizumab Combination Therapy in Participants With Active Rheumatoid Arthritis

NCT06028438

COMPLETED Phase 2

A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

NCT05811351

TERMINATED Phase 3

A Study of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection

NCT05784129

COMPLETED

A Study to Investigate Acute Respiratory Virus Infections in Participants at High Risk for Severe Illness

NCT05661604

COMPLETED Phase 1

A Study of Four Different Oral Tablet Formulations of Lazertinib (JNJ-73841937) in Healthy Adult Participants

NCT05742594

COMPLETED Phase 3

A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

NCT05550532

COMPLETED Phase 1

A Study of JNJ-80038114 in Participants With Advanced Stage Prostate Cancer

NCT05441501

COMPLETED Phase 1

A Single Ascending Dose Study of JNJ-88260237 in Healthy Participants

NCT05541315

COMPLETED Phase 1

A Study to Assess the Acceptability of the Darunavir/Cobicistat (DRV/COBI) Fixed-dose Combination (FDC) Tablet in Human Immunodeficiency Virus (HIV)-1 Infected Children

NCT05197075

COMPLETED Phase 1

A Study of VAC85135, a Neoantigen Vaccine Regimen, Concurrently Administered With Ipilimumab for the Treatment of Myeloproliferative Neoplasms

NCT05444530

COMPLETED Phase 3

Study of Guselkumab in Skin of Color Participants With Moderate-to-severe Plaque and/or Scalp Psoriasis

NCT05272150

COMPLETED Phase 3

A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

NCT05455684

COMPLETED Phase 2

A Study of JNJ-77242113 for the Treatment of Moderate-to-Severe Plaque Psoriasis

NCT05357755

COMPLETED Phase 2

A Long-term Extension Study of JNJ-77242113 in Participants With Moderate-to-Severe Plaque Psoriasis

NCT05364554

COMPLETED Phase 1

A Study of Ustekinumab in Pediatric Participants (U-POPS) With Juvenile Psoriatic Arthritis or Psoriasis

NCT05252533

COMPLETED Phase 2

A Study of Seltorexant in Participants With Probable Alzheimer's Disease

NCT05307692

COMPLETED

A Study to Examine Biomarkers From Lung and Blood Samples in Participants With Suspected Lung Cancer

NCT04951154

TERMINATED Phase 1

A Study of EPI-7386 in Combination With Abiraterone Acetate Plus Prednisone, or Apalutamide in Metastatic Castration-resistant Prostate Cancer (mCRPC)

NCT05295927

COMPLETED

A Study of Ustekinumab Treatment in Children With Crohn's Disease

NCT05242458

COMPLETED Phase 2

A Study of JNJ-77242113 in Participants With Moderate-to-severe Plaque Psoriasis

NCT05223868

COMPLETED Early Phase 1

A Study of Acute Respiratory Infections in Global Outpatient Setting

NCT05148780

COMPLETED Phase 1

A Study to Determine the Abuse Potential of Seltorexant Compared to Suvorexant and Zolpidem

NCT05106153

TERMINATED Phase 2

A Study of Rilematovir (JNJ-53718678) in Adult Outpatients With Respiratory Syncytial Virus (RSV) Infection

NCT04978337

COMPLETED Phase 1

A Study of a Rilpivirine Extended-Release Suspension in Healthy Participants

NCT05112939

COMPLETED Phase 1

A Study of JNJ-64251330 in Participants With Familial Adenomatous Polyposis

NCT05014360

TERMINATED Phase 2

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis B Virus Infection

NCT05005507

COMPLETED

A Study of Pentosan Polysulfate Sodium and the Development of Pigmentary Maculopathy and Pigmentary Retinopathy

NCT05179460

TERMINATED

A Standard of Care Study of Patients With Major Depressive Disorder Who Have Had an Inadequate Response to a Selective Serotonin Reuptake/Serotonin-Norepinephrine Reuptake Inhibitor Antidepressant

NCT05109195

COMPLETED Phase 2

A Study of Guselkumab and Golimumab Combination Therapy in Participants With Active Psoriatic Arthritis

NCT05071664

COMPLETED Phase 1

A Study of JNJ-67484703 in Participants With Active Rheumatoid Arthritis

NCT04985812

COMPLETED Phase 2

A Proof-of-concept Study of the Efficacy and Safety of Nipocalimab in Participants With Active Rheumatoid Arthritis

NCT04991753

TERMINATED Phase 2

A Study of Bermekimab for the Treatment of Participants With Moderate to Severe Hidradenitis Suppurativa

NCT04988308

COMPLETED Phase 2

A Study of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS)

NCT04968912

COMPLETED Phase 1

A Study of Lazertinib (JNJ-73841937) in Healthy Participants

NCT05076877

TERMINATED Phase 3

A Study of Rilematovir in Infants and Children and Subsequently in Neonates Hospitalized With Acute Respiratory Tract Infection Due to Respiratory Syncytial Virus (RSV)

NCT04583280

TERMINATED Phase 2

A Study of Bermekimab for the Treatment of Adult Participants With Moderate-to-Severe Atopic Dermatitis

NCT04990440

TERMINATED Phase 1

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy

NCT04951609

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Phase Distribution

PhaseTrial count
Phase 1 225
Phase 2 152
Phase 3 173
Phase 4 6

What the Pipeline for Janssen Research & Development Shows

According to the ClinicalTrials.gov registry, Janssen Research & Development is linked to 593 US clinical trials across every stage of research activity. Of those, 68 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 384 are already marked complete, representing roughly 65% of the total.

The phase mix for Janssen Research & Development reports 179 late-stage studies (Phase 3 and Phase 4 combined) and 377 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Janssen Research & Development is Healthy with 25 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.