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NCT03399799 · ClinicalTrials.gov registry record · Phase 1
Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma
A Phase 1 study of Hematological Malignancies, sponsored by Janssen Research & Development.
- Active
- Registry status
- Phase 1
- Development phase
- 279
- Enrollment target
- 13
- Study locations
NCT03399799 is a Phase 1 study of Hematological Malignancies that is active but no longer recruiting, run by Janssen Research & Development. The registered enrollment target is 279 participants, below the 759-participant average among 16 other Hematological Malignancies trials with a reported enrollment target (63% lower). The trial reports 13 study locations across 6 states.
The verdict
NCT03399799, a Phase 1 study of Hematological Malignancies, is active but no longer recruiting, sponsored by Janssen Research & Development.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 279 participants
- Enrollment target
- 13
- Study locations
Study Summary
The purpose of this study is to characterize the safety of Talquetamab and to determine the recommended Phase 2 dose(s) (RP2Ds) and dosing schedule assessed to be safe for Talquetamab (Part 1 \[Dose Escalation\]) and to further characterize the safety of Talquetamab at the recommended Phase 2 dose(s) (RP2Ds) (Part 2 \[Dose Expansion\]).
Conditions Studied
Interventions
- DRUG Talquetamab
Study Locations (13)
Other
- Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman - Liège
- VU Medisch Centrum - Amsterdam
- UMCU - Utrecht
- Hosp. Univ. Germans Trias I Pujol - Badalona
- Hosp Univ Fund Jimenez Diaz - Madrid
- Clinica Univ. de Navarra - Pamplona
- Hosp. Quiron Madrid Pozuelo - Pozuelo de Alarcón
- Hosp Clinico Univ de Salamanca - Salamanca
Alabama
- University of Alabama Birmingham - Birmingham
California
- City of Hope - Duarte
Colorado
- University of Colorado Cancer Center - Aurora
New York
- Mount Sinai Medical Center - New York
Tennessee
- Tennessee Oncology - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 279 participants |
| Start Date | 2017-12-16 |
| Est. Completion | 2027-10-20 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03399799
The ClinicalTrials.gov registry entry for NCT03399799 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 279 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 759-participant average among 16 other Hematological Malignancies trials with a reported enrollment target (63% lower). The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hematological Malignancies appearing as the primary indexed condition, and to 1 intervention - of which Talquetamab is the first listed.
NCT03399799 reports 13 study locations spanning 6 distinct geographic areas - top geographies include Other, Alabama, California.
Frequently Asked Questions
What is clinical trial NCT03399799 about?
NCT03399799 is a clinical study titled "Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma". The purpose of this study is to characterize the safety of Talquetamab and to determine the recommended Phase 2 dose(s) (RP2Ds) and dosing schedule assessed to be safe for Talquetamab (Part 1 \[Dose Escalation\]) and to further characterize the safety of Talquetamab at the recommended Phase 2 dose(s...
What is the current status of trial NCT03399799?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 279 participants. The study started on 2017-12-16. Estimated completion is 2027-10-20.
What conditions does trial NCT03399799 study?
This clinical trial studies the following conditions: Hematological Malignancies.
What interventions are being tested in trial NCT03399799?
The interventions under investigation include: Talquetamab (DRUG).
Who is sponsoring clinical trial NCT03399799?
This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03399799 being conducted?
This trial has 13 study locations across Alabama, California, Colorado, New York, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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