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NCT06635135 · ClinicalTrials.gov registry record · Phase 3

A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

A Phase 3 study, sponsored by Janssen Research & Development.

Terminated
Registry status
Phase 3
Development phase
47
Enrollment target

NCT06635135 is a Phase 3 study that was terminated before completion, run by Janssen Research & Development. The registered enrollment target is 47 participants.

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The verdict

NCT06635135, a Phase 3 study, was terminated before completion, sponsored by Janssen Research & Development.

TERMINATED
Registry status
Phase 3
Development phase
47 participants
Enrollment target

Study Summary

The purpose of this study is to assess how well aticaprant works compared to placebo when given in addition to antidepressant therapy (selective serotonin reuptake inhibitor \[SSRI\] or serotonin-norepinephrine reuptake inhibitor \[SNRI\]) in preventing return of depression symptoms in participants with major depressive disorder who experience a loss of interest and pleasure and who achieve a stable response after treatment with adjunctive aticaprant.

Interventions

  • OTHER Placebo
  • DRUG Aticaprant

Trial Details

FieldValue
Enrollment Target 47 participants
Start Date 2024-09-19
Est. Completion 2025-04-25
Phase Phase 3

Sponsor

Janssen Research & Development

593 total trials

What the Registry Record Tells You About NCT06635135

The ClinicalTrials.gov registry entry for NCT06635135 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 47 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT06635135 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06635135 about?

NCT06635135 is a clinical study titled "A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure". The purpose of this study is to assess how well aticaprant works compared to placebo when given in addition to antidepressant therapy (selective serotonin reuptake inhibitor \[SSRI\] or serotonin-norepinephrine reuptake inhibitor \[SNRI\]) in preventing return of depression symptoms in participants ...

What is the current status of trial NCT06635135?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 47 participants. The study started on 2024-09-19. Estimated completion is 2025-04-25.

What interventions are being tested in trial NCT06635135?

The interventions under investigation include: Placebo (OTHER), Aticaprant (DRUG).

Who is sponsoring clinical trial NCT06635135?

This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.