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NCT04470622 · ClinicalTrials.gov registry record · Phase 2
Aprepitant Injectable Emulsion in Patients With COVID-19 (GUARDS-1)
A Phase 2 study, sponsored by Heron Therapeutics.
- Terminated
- Registry status
- Phase 2
- Development phase
- 27
- Enrollment target
NCT04470622: Clinical Trial Phase 2 study, sponsored by Heron Therapeutics.
NCT04470622 is a Phase 2 study that was terminated before completion, run by Heron Therapeutics. The registered enrollment target is 27 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04470622, a Phase 2 study, was terminated before completion, sponsored by Heron Therapeutics.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 27 participants
- Enrollment target
Study Summary
The study will evaluate the efficacy and safety of aprepitant injectable emulsion added to standard of care for hospitalized patients with COVID-19.
Primary Outcome
ITT Population.
Interventions
- DRUG Saline Placebo
- DRUG Aprepitant injectable emulsion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2020-07-20 |
| Est. Completion | 2021-06-03 |
| Phase | Phase 2 |
Why NCT04470622 stopped before completion
NCT04470622 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 2 interventions - of which Saline Placebo is the first listed.
NCT04470622 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04470622 about?
NCT04470622 is a clinical study titled "Aprepitant Injectable Emulsion in Patients With COVID-19 (GUARDS-1)". The study will evaluate the efficacy and safety of aprepitant injectable emulsion added to standard of care for hospitalized patients with COVID-19.
What is the current status of trial NCT04470622?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2020-07-20. Estimated completion is 2021-06-03.
What interventions are being tested in trial NCT04470622?
The interventions under investigation include: Saline Placebo (DRUG), Aprepitant injectable emulsion (DRUG).
Who is sponsoring clinical trial NCT04470622?
This trial is sponsored by Heron Therapeutics, which has 23 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04470622's enrollment target sits among peer trials
27 1697th of 2000 higher than 293 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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