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NCT03974932 · ClinicalTrials.gov registry record · Phase 3
Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen
A Phase 3 study, sponsored by Heron Therapeutics.
- Completed
- Registry status
- Phase 3
- Development phase
- 116
- Enrollment target
NCT03974932: Completed Phase 3 study, sponsored by Heron Therapeutics.
NCT03974932 is a Phase 3 study that has completed, run by Heron Therapeutics. The registered enrollment target is 116 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03974932, a Phase 3 study, has completed, sponsored by Heron Therapeutics.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 116 participants
- Enrollment target
Study Summary
Phase 3b, open-label single-arm study in which all subjects receive HTX-011 as part of a scheduled non-opioid MMA regimen.
Primary Outcome
The Visual Analog Scale (VAS) consists of a straight 10-cm line that represents pain ranging from "no pain" to "pain as bad as it could be". Subjects were asked to mark their current pain level on the line.
Interventions
- DRUG Acetaminophen
- DRUG Ibuprofen
- DRUG Celecoxib
- DRUG HTX-011
- DRUG +/- Bupivacaine HCl
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 116 participants |
| Start Date | 2019-06-05 |
| Est. Completion | 2021-01-07 |
| Phase | Phase 3 |
What the finished NCT03974932 record still lists
NCT03974932 is an interventional study that assigns participants to a tested intervention. The registered 116 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 5 interventions - of which Acetaminophen is the first listed.
NCT03974932 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03974932 about?
NCT03974932 is a clinical study titled "Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen". Phase 3b, open-label single-arm study in which all subjects receive HTX-011 as part of a scheduled non-opioid MMA regimen.
What is the current status of trial NCT03974932?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 116 participants. The study started on 2019-06-05. Estimated completion is 2021-01-07.
What interventions are being tested in trial NCT03974932?
The interventions under investigation include: Acetaminophen (DRUG), Ibuprofen (DRUG), Celecoxib (DRUG), HTX-011 (DRUG), +/- Bupivacaine HCl (DRUG).
Who is sponsoring clinical trial NCT03974932?
This trial is sponsored by Heron Therapeutics, which has 23 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03974932's enrollment target sits among peer trials
116 1643rd of 2000 higher than 357 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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