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NCT04398329 · ClinicalTrials.gov registry record · Phase 1

Dose-Escalation Study of HTX-034 Following Bunionectomy

A Phase 1 study, sponsored by Heron Therapeutics.

Completed
Registry status
Phase 1
Development phase
78
Enrollment target

NCT04398329 is a Phase 1 study that has completed, run by Heron Therapeutics. The registered enrollment target is 78 participants.

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The verdict

NCT04398329, a Phase 1 study, has completed, sponsored by Heron Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
78 participants
Enrollment target

Study Summary

This was a Phase 1b/2, randomized, blinded, active-controlled study. Phase 1b evaluated escalating doses of HTX-034 compared with bupivacaine HCl. Phase 2 was a dose-expansion phase to evaluate additional subjects treated with the HTX-034 dose selected based on Phase 1b, compared with bupivacaine HCl.

Interventions

  • DRUG Bupivacaine HCl
  • DRUG HTX-034 low dose
  • DRUG HTX-034 high dose
  • DEVICE Luer lock applicator

Trial Details

FieldValue
Enrollment Target 78 participants
Start Date 2020-05-08
Est. Completion 2021-07-15
Phase Phase 1

Sponsor

Heron Therapeutics

23 total trials

What the Registry Record Tells You About NCT04398329

The ClinicalTrials.gov registry entry for NCT04398329 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 78 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Heron Therapeutics, which has 23 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Bupivacaine HCl is the first listed.

NCT04398329 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04398329 about?

NCT04398329 is a clinical study titled "Dose-Escalation Study of HTX-034 Following Bunionectomy". This was a Phase 1b/2, randomized, blinded, active-controlled study. Phase 1b evaluated escalating doses of HTX-034 compared with bupivacaine HCl. Phase 2 was a dose-expansion phase to evaluate additional subjects treated with the HTX-034 dose selected based on Phase 1b, compared with bupivacaine HC...

What is the current status of trial NCT04398329?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 78 participants. The study started on 2020-05-08. Estimated completion is 2021-07-15.

What interventions are being tested in trial NCT04398329?

The interventions under investigation include: Bupivacaine HCl (DRUG), HTX-034 low dose (DRUG), HTX-034 high dose (DRUG), Luer lock applicator (DEVICE).

Who is sponsoring clinical trial NCT04398329?

This trial is sponsored by Heron Therapeutics, which has 23 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.