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NCT00705406 · ClinicalTrials.gov registry record · Phase 2

A Phase II, Multicenter, Randomized, Placebo -Controlled, Study To Evaluate The Efficacy and Safety Of Intramuscular Peramivir 600 mg In Subjects With Uncomplicated Acute Influenza

A Phase 2 study, sponsored by BioCryst Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
405
Enrollment target

NCT00705406: Completed Phase 2 study, sponsored by BioCryst Pharmaceuticals.

NCT00705406 is a Phase 2 study that has completed, run by BioCryst Pharmaceuticals. The registered enrollment target is 405 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (205% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00705406, a Phase 2 study, has completed, sponsored by BioCryst Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
405 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether peramivir is safe and effective in the treatment of uncomplicated seasonal influenza.

Primary Outcome

The primary efficacy endpoint was the time to alleviation of symptoms calculated as the number of hours from initiation of study drug until the start of the time period in which all 7 symptoms of influenza were either absent or present at a level no greater than mild for at least 21.5 (24 hours - 10%) hours. Subjects with missing diary data were excluded and those who did not experience alleviation of symptoms were censored at the last observed symptom assessment.

Interventions

  • DRUG Placebo
  • DRUG Peramivir

Trial Details

FieldValue
Enrollment Target 405 participants
Start Date 2008-07
Est. Completion 2009-10
Phase Phase 2
BioCryst Pharmaceuticals

29 total trials

What the finished NCT00705406 record still lists

NCT00705406 is an interventional study that assigns participants to a tested intervention. The registered 405 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (205% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00705406 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00705406 about?

NCT00705406 is a clinical study titled "A Phase II, Multicenter, Randomized, Placebo -Controlled, Study To Evaluate The Efficacy and Safety Of Intramuscular Peramivir 600 mg In Subjects With Uncomplicated Acute Influenza". The purpose of this study is to determine whether peramivir is safe and effective in the treatment of uncomplicated seasonal influenza.

What is the current status of trial NCT00705406?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 405 participants. The study started on 2008-07. Estimated completion is 2009-10.

What interventions are being tested in trial NCT00705406?

The interventions under investigation include: Placebo (DRUG), Peramivir (DRUG).

Who is sponsoring clinical trial NCT00705406?

This trial is sponsored by BioCryst Pharmaceuticals, which has 29 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00705406's enrollment target sits among peer trials

405 95th of 2000 higher than 1,906 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00705406, the US trial registry maintained by the National Library of Medicine. NCT00705406 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.