Bayer

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Bayer sits in the top decile of US sponsors by registered trial count (#58 of 15,742 sponsors by registered trial count).

591 total trials 21 currently recruiting 494 completed top decile by trial count

Bayer: 591 sponsored US clinical trials, 21 recruiting.

Bayer sponsors 591 registered US clinical trials on ClinicalTrials.gov, 21 of them currently recruiting, and 494 completed. 172 of these trials are in Phase 3-4 (later-stage) and 237 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sunscreening Agents, with 17 trials.

Top-decile sponsor footprint

Bayer ranks in the top decile of sponsors by registered trial count (#58 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 63/100

494 of 552 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

591 total, page 9 of 12

COMPLETED Phase 3

Actual Use Trial of Naproxen Sodium

NCT01427803

COMPLETED Phase 1

Phase I Study of PI3(Phosphoinositol 3)-Kinase Inhibitor BAY80-6946 With Paclitaxel in Patients With Advanced Cancer

NCT01411410

COMPLETED Phase 1

Phase Ib Study of PI3(Phosphoinositol 3)-Kinase Inhibitor Copanlisib With MEK (Mitogen-activated Protein Kinase) Inhibitor Refametinib (BAY86-9766) in Patients With Advanced Cancer

NCT01392521

COMPLETED Phase 3

Self Selection Trial of Naproxen Sodium

NCT01383486

COMPLETED Phase 3

Evaluate Onset of Action of a Fast Release Aspirin

NCT01420094

COMPLETED Phase 3

BAY81-8973 Pediatric Safety and Efficacy Trial

NCT01311648

COMPLETED Phase 3

Evaluate Efficacy and Safety of Extended Release (ER) Naproxen Sodium

NCT01389284

COMPLETED Phase 4

Essure Transvaginal Ultrasound (TVU) Study

NCT01327105

COMPLETED Phase 3

Gadobutrol Enhanced MRA of the Supra-aortic Vessels

NCT01344447

COMPLETED Phase 1

Vardenafil ODT (Orally Disintegrating Tablet) - Nifedipine Interaction Study

NCT01348880

COMPLETED Phase 3

Safety Trial of Naproxen Sodium/ Diphenhydramine

NCT01365052

COMPLETED Phase 3

Gadobutrol Enhanced MRA of the Renal Arteries

NCT01344460

COMPLETED Phase 2

Study of Nifedipine GITS and Candesartan Combination Compared to Monotherapy in Patients With Essential Hypertension

NCT01303783

COMPLETED Phase 1

Open Label Regorafenib Study to Evaluate Cardiovascular Safety Parameters, Tolerability, and Anti-tumor Activity

NCT01339104

COMPLETED Phase 1

Effect of Ketoconazole on Regorafenib (BAY73-4506) Pharmacokinetics

NCT01318265

COMPLETED Phase 1

Effect of Rifampin on the Pharmacokinetics of BAY73-4506

NCT01322438

COMPLETED Phase 3

Phase III Trial Comparing Capecitabine in Combination With Sorafenib or Placebo in the Treatment of Locally Advanced or Metastatic HER2-Negative Breast Cancer

NCT01234337

COMPLETED Phase 2

First Line Treatment of Metastatic Colorectal Cancer With mFOLFOX6 in Combination With Regorafenib

NCT01289821

COMPLETED Phase 3

LCS12 vs Combined Oral Contraceptive (COC) User Satisfaction Study

NCT01254292

COMPLETED Phase 3

Study of Regorafenib as a 3rd-line or Beyond Treatment for Gastrointestinal Stromal Tumors (GIST)

NCT01271712

COMPLETED Phase 1

Combination With Gemcitabine in Advanced Pancreatic Cancer

NCT01251640

COMPLETED Phase 3

A Trial to Compare Prophylaxis Therapy to On-demand Therapy With a New Full Length Recombinant FVIII in Patients With Severe Hemophilia A

NCT01233258

COMPLETED Phase 1

Clinical Study to Evaluate Safety and Maximum Tolerated Dose of BAY1000394 Given in a 4 Week on / 2 Week Off Schedule in Subjects With Advanced Malignancies

NCT01335256

COMPLETED Phase 2

Efficacy and Safety of Different Concentrations of ZK245186 in Atopic Dermatitis (AD)

NCT01228513

COMPLETED Phase 1

Rivaroxaban Pharmacokinetics/Pharmacodynamics (PK/PD) Study in Pediatric Subjects

NCT01145859

TERMINATED Phase 2

Hemodynamic and Echocardiographic Assessment of Riociguat Effects on Myocardial Wall Contractility and Relaxation Kinetics

NCT01065051

COMPLETED Phase 1

Trial to Evaluate the Pharmacokinetics and Safety Profile of BAY94-9027 Following Single and Multiple Dose Administration

NCT01184820

COMPLETED Phase 3

Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine in Patients With Postsurgical Dental Pain

NCT01280591

COMPLETED Phase 2

Evaluation of the Pharmacodynamic Effect of the Combination of Sildenafil and Riociguat on Blood Pressure and Other Safety Parameters.

NCT01179334

COMPLETED Phase 1

Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 Given in a 3 Days on / 4 Days Off Schedule in Subjects With Advanced Malignancies

NCT01188252

TERMINATED Phase 1

Determination of Safety, Efficacy, and Pharmacokinetics of "Regorafenib" Combined With Pemetrexed and Cisplatin in Patients With Nonsquamous Non-Small Cell Lung Cancer

NCT01187615

COMPLETED Phase 3

Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection

NCT01069900

COMPLETED Phase 1

A Study of Alpharadin With Docetaxel in Patients With Bone Metastasis From Castration-Resistant Prostate Cancer (CRPC)

NCT01106352

COMPLETED Phase 3

Study to Gather Information About the Actual Use of an Adhesive Patch Placed on the Skin to Deliver Oxytrol Through the Skin Into the Bloodstream.

NCT04534491

COMPLETED Phase 1

Safety, Tolerability and Pharmacokinetics of Single Dose Intravenous Moxifloxacin in Pediatric Patients

NCT01049022

COMPLETED Phase 3

Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast Magnetic Resonance Imaging (MRI)

NCT01104584

COMPLETED Phase 3

Evaluate Analgesic Efficacy of Fast Release Aspirin

NCT01122602

COMPLETED Phase 3

Evaluate Analgesic Efficacy of Fast Release Aspirin

NCT01117636

COMPLETED Phase 2

A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction

NCT01065454

COMPLETED Phase 3

Patients With Metastatic Colorectal Cancer Treated With Regorafenib or Placebo After Failure of Standard Therapy

NCT01103323

TERMINATED Phase 2

A Phase IIb Study to Investigate the Efficacy and Tolerability of Cinaciguat (150 µg/h, 100 µg/h, 50 µg/h) Given Intravenously to Subjects With Acute Decompensated Chronic Congestive Heart Failure (ADHF)

NCT01064037

TERMINATED Phase 2

BAY58-2667 Dose Finding Trial Investigating Fixed Doses in Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF)

NCT01065077

TERMINATED Phase 2

A Phase IIb Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 µg/h, 10 µg/h) Given Intravenously to Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF)

NCT01067859

COMPLETED Phase 3

Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast MRI

NCT01067976

COMPLETED Phase 1

Pharmacokinetic Study Comparing Aspirin and Effervescent Aspirin

NCT01081353

COMPLETED

Telephone Interview of Patients That Participated in the the Pivotal Betaferon MS Trial.

NCT01031459

COMPLETED Phase 3

Contrast-enhanced MRI in Children 2 Months to <2 Years

NCT00937391

COMPLETED Phase 3

Trial to Evaluate the Efficacy and Safety of a New Full Length Recombinant Human FVIII for Hemophilia A

NCT01029340

COMPLETED

Liver MRI With Primovist/Eovist in Pediatric Subjects Who Are Suspected or Have Focal Liver Lesions.

NCT01043523

COMPLETED Phase 1

BAY80-6946 Open Label, Phase I Study in Patients With Advanced Cancer

NCT00962611

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What is open in the Bayer pipeline

21 recruiting of 591 indexed (4% open); 494 completed (84%).

Phase mix: 172 late (III/IV) vs 237 early (I/II) (balanced across stages).

Top condition: Sunscreening Agents (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Bayer: open-pipeline peers nationwide

Peers matched on 591 registered trials and 4% open enrollment, not the therapeutic-area sidebar.

Bayer sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%10%20%30% Total trials Recruiting share BayerJanssen Research & DevelopmentCity of Hope Medical CenterChildren's Hospital Medical Center, CincinnatiNational Institute of Neurological Disorders and Stroke (NINDS)Bausch Health AmericasHarvard Pilgrim Health CareSumitomo Pharma AmericaTeva Branded Pharmaceutical Products R&D
Bayer sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Bayer sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 591 trials (± recruiting share)

Sponsors near 4% open enrollment (± trial volume)

What to do with this Bayer page

591 registered trials is a research-attention snapshot, not an endorsement of Bayer or any single study.

  • 21 of Bayer's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Sunscreening Agents is the condition Bayer studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Sunscreening Agents trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Bayer pipeline card: 591 registered trials from official public datasets.Report a data error.