Bayer

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Bayer sits in the top decile of US sponsors by registered trial count (#58 of 15,742 sponsors by registered trial count).

591 total trials 21 currently recruiting 494 completed top decile by trial count

Bayer: 591 sponsored US clinical trials, 21 recruiting.

Bayer sponsors 591 registered US clinical trials on ClinicalTrials.gov, 21 of them currently recruiting, and 494 completed. 172 of these trials are in Phase 3-4 (later-stage) and 237 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sunscreening Agents, with 17 trials.

Top-decile sponsor footprint

Bayer ranks in the top decile of sponsors by registered trial count (#58 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 63/100

494 of 552 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

591 total, page 10 of 12

COMPLETED Phase 1

To Determine Maximum Tolerated Dose of BAY79-4620 in Patients With Advanced Solid Tumors

NCT01028755

COMPLETED Phase 3

Nexavar® Versus Placebo in Locally Advanced/Metastatic RAI-Refractory Differentiated Thyroid Cancer

NCT00984282

COMPLETED Phase 1

The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib

NCT01002378

TERMINATED Phase 4

PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)

NCT00867815

COMPLETED Phase 3

BAY63-2521 - Long-term Extension Study in Patients With Chronic Thromboembolic Pulmonary Hypertension

NCT00910429

COMPLETED Phase 1

Cipro Inhaler for Cystic Fibrosis Children Ages 6-12

NCT00910351

COMPLETED Phase 1

Pharmacokinetic Study Comparing Aspirin and Aspirin Granules

NCT01072604

COMPLETED Phase 3

US Cycle Control and Blood Pressure Study

NCT00920985

COMPLETED Phase 2

Evaluation of Cipro Inhale in Patients With Non-cystic Fibrosis Bronchiectasis

NCT00930982

COMPLETED Phase 3

Nexavar-Tarceva Combination Therapy for First Line Treatment of Patients Diagnosed With Hepatocellular Carcinoma

NCT00901901

COMPLETED Phase 3

Study Investigating the Efficacy and Safety of a Contraceptive Patch for 13 Cycles

NCT00910637

COMPLETED Phase 4

Primovist / Eovist in Renally Impaired Patients

NCT00908596

COMPLETED Phase 2

US Ovulation Inhibition Study in Obese Women

NCT00873483

COMPLETED Phase 1

Pharmacokinetics Study Comparing Naproxen Sodium Extended Release and Naprelan

NCT00969449

COMPLETED Phase 3

A 3rd/4th Line Placebo-controlled Trial of Sorafenib in Patients With Predominantly Non Squamous Non-Small Cell Lung Cancer (NSCLC).

NCT00863746

COMPLETED Phase 3

Effect on Primary Dysmenorrhea

NCT00909857

COMPLETED Phase 3

BAY63-2521:Long-term Extension Study in Patients With Pulmonary Arterial Hypertension

NCT00863681

COMPLETED Phase 2

Study of Modified FOLFOX6 Plus or Minus Sorafenib in Stage IV Metastatic Colorectal Carcinoma (mCRC) Subjects

NCT00865709

COMPLETED Phase 2

A Phase II Randomized, Double-blind, Placebo-controlled Study of Sorafenib or Placebo in Combination With Transarterial Chemoembolization (TACE) Performed With DC Bead and Doxorubicin for Intermediate Stage Hepatocellular Carcinoma (HCC).

NCT00855218

COMPLETED Phase 3

A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With CTEPH.

NCT00855465

COMPLETED Phase 1

Hepatic Impairment Study

NCT00829231

COMPLETED

Global Investigation of Therapeutic Decisions in Hepatocellular Carcinoma and of Its Treatment With Sorafenib

NCT00812175

COMPLETED Phase 3

A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With Pulmonary Arterial Hypertension (PAH)

NCT00810693

COMPLETED Phase 2

Comparison of Nexavar/Placebo as Maintenance Therapy for Patients With Advanced Ovarian or Primary Peritoneal Cancer

NCT00791778

COMPLETED Phase 1

RDEA119 and Sorafenib Combination Dose Escalation Study

NCT00785226

COMPLETED

Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Moderate Renal Insufficiency After the Administration of Magnevist

NCT00744939

COMPLETED Phase 1

Naproxen Sodium ER Pharmacokinetic Study

NCT00818415

COMPLETED Phase 3

To Compare SH T00658ID Over Ortho Tri-Cyclen Lo (US/Canada)

NCT00754065

COMPLETED Phase 3

Sorafenib as Adjuvant Treatment in the Prevention Of Recurrence of Hepatocellular Carcinoma (STORM)

NCT00692770

COMPLETED Phase 1

Alpharadin™ (Radium-223 Chloride) Safety and Dosimetry With HRPC That Has Metastasized to the Skeleton

NCT00748046

COMPLETED Phase 3

Naproxen Sodium Extended-Release Actual Use Study

NCT00751400

COMPLETED Phase 3

A Phase III Study of Radium-223 Dichloride in Patients With Symptomatic Hormone Refractory Prostate Cancer With Skeletal Metastases

NCT00699751

COMPLETED Phase 3

Assessing the Analgesic Efficacy of Naproxen Sodium in Postsurgical Dental Pain.

NCT00720057

COMPLETED Phase 3

Safety and Efficacy of Gadobutrol 1.0 Molar (Gadavist) in Patients for Central Nervous System (CNS) Imaging

NCT00709852

TERMINATED Phase 2

BAY79-4980 Compared to rFVIII-FS in Previously Treated Patients With Severe Hemophilia A

NCT00623727

COMPLETED Phase 2

Study to Evaluate the Safety and Efficacy of Ciprofloxacin (Inhaled) in Patients With Cystic Fibrosis

NCT00645788

TERMINATED Phase 1

Mechanistic Evaluation on Sorafenib Induced Hypophosphatemia.

NCT00622479

COMPLETED Phase 2

A Phase II Uncontrolled Study of BAY73-4506 in Previously Untreated Patients With Metastatic or Unresectable RCC

NCT00664326

COMPLETED Phase 3

Vardenafil Orodispersible Tablet (ODT) Versus Placebo in Males With Erectile Dysfunction, 50% of Whom Are to be 65 Years or Older.

NCT00655629

COMPLETED Phase 3

Trial to Evaluate the Effect of Secondary Prophylaxis With rFVIII Therapy in Severe Hemophilia A Adult and/or Adolescent Subjects Compared to That of Episodic Treatment

NCT00623480

COMPLETED Phase 1

Single/Multiple Dose Bioavailability Trial

NCT00751556

COMPLETED Phase 1

Fast & Fed Pharmacokinetic (PK) Study

NCT00692016

COMPLETED Phase 4

Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine

NCT01118273

COMPLETED Phase 3

Sorafenib Long Term Extension Program

NCT00625378

COMPLETED

Evaluation of the Reasons and Consequences of Bleeding in Late Teens and Early Adulthood Patients With Severe Hemophilia A

NCT00782470

COMPLETED Phase 3

Venous Thromboembolic Event (VTE) Prophylaxis in Medically Ill Patients

NCT00571649

COMPLETED Phase 3

Safety and Efficacy of Gadobutrol 1.0 Molar ( Gadavist ) in Patients for Central Nervous System (CNS) Imaging

NCT00623467

TERMINATED Phase 2

Placebo Controlled, Randomized, Double-blind, Multi-center Study to Investigate the Efficacy and Tolerability of BAY58-2667

NCT00559650

COMPLETED Phase 1

Phase 1 Dose-escalation PK/PD Trial in Advanced Cancer Patients

NCT00610194

COMPLETED Phase 1

Sorafenib/Docetaxel Dose Escalation Trial

NCT00562523

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What is open in the Bayer pipeline

21 recruiting of 591 indexed (4% open); 494 completed (84%).

Phase mix: 172 late (III/IV) vs 237 early (I/II) (balanced across stages).

Top condition: Sunscreening Agents (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Bayer: open-pipeline peers nationwide

Peers matched on 591 registered trials and 4% open enrollment, not the therapeutic-area sidebar.

Bayer sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%10%20%30% Total trials Recruiting share BayerJanssen Research & DevelopmentCity of Hope Medical CenterChildren's Hospital Medical Center, CincinnatiNational Institute of Neurological Disorders and Stroke (NINDS)Bausch Health AmericasHarvard Pilgrim Health CareSumitomo Pharma AmericaTeva Branded Pharmaceutical Products R&D
Bayer sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Bayer sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 591 trials (± recruiting share)

Sponsors near 4% open enrollment (± trial volume)

What to do with this Bayer page

591 registered trials is a research-attention snapshot, not an endorsement of Bayer or any single study.

  • 21 of Bayer's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Sunscreening Agents is the condition Bayer studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Sunscreening Agents trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Bayer pipeline card: 591 registered trials from official public datasets.Report a data error.