AEterna Zentaris

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, AEterna Zentaris sits in the top decile of US sponsors by registered trial count (#714 of 15,742 sponsors by registered trial count).

21 total trials none currently recruiting 17 completed early-phase tilt top decile by trial count

AEterna Zentaris: 21 sponsored US clinical trials, none currently recruiting.

AEterna Zentaris sponsors 21 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 17 completed. 8 of these trials are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Benign Prostatic Hypertrophy, with 1 trials.

Top-decile sponsor footprint

AEterna Zentaris ranks in the top decile of sponsors by registered trial count (#714 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 42/100

17 of 21 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

21 total, page 1 of 1

COMPLETED Phase 3

A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How Safe it is

NCT04786873

COMPLETED Phase 3

Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency

NCT02558829

COMPLETED Phase 3

Zoptarelin Doxorubicin (AEZS 108) as Second Line Therapy for Endometrial Cancer

NCT01767155

TERMINATED Phase 2

Phase 2 Trial of AEZS-108 in Chemotherapy Refractory in Triple Negative Breast Cancer

NCT01698281

COMPLETED Phase 1

A Food Effect and QTc Study of Perifosine in Patients With Advanced Malignancies

NCT01224730

TERMINATED Phase 1

A Phase I/II Trial of AEZS-108 in Urothelial Cancer Patients Who Failed Platinum-chemotherapy

NCT01234519

COMPLETED Phase 3

Perifosine Plus Capecitabine Versus Placebo Plus Capecitabine in Patients With Refractory Advanced Colorectal Cancer

NCT01097018

TERMINATED Phase 3

Assessment of Efficacy and Safety of Perifosine, Bortezomib and Dexamethasone in Multiple Myeloma Patients

NCT01002248

COMPLETED Phase 3

Cetrorelix Pamoate IM Regimens in Patients With Symptomatic Benign Prostatic Hyperplasia (BPH)

NCT00670306

COMPLETED Phase 2

Ph II Study of Perifosine for Patients With Carcinoma of the Kidney

NCT00498966

COMPLETED Phase 3

Investigation of a New, Oral Growth Hormone Secretagogue, AEZS-130 as a Growth Hormone Stimulation Test.

NCT00448747

COMPLETED Phase 2

A Phase II Trial of Perifosine Following Tyrosine Kinase Inhibitor (TKI) - Failure in Patients With Renal Cancer

NCT00448721

TERMINATED Phase 3

Cetrorelix (CET) Pamoate Regimens in Patients With Symptomatic Benign Prostatic Hypertrophy (BPH)

NCT00449150

COMPLETED Phase 1

Phase I Study of Perifosine + Lenalidomide and Dexamethasone for Patients With Multiple Myeloma

NCT00415064

COMPLETED Phase 2

A Phase II Study of Perifosine in Patients With Relapsed/Refractory Waldenström's Macroglobulinemia

NCT00398710

COMPLETED Phase 2

Efficacy of Perifosine Alone and in Combination With Dexamethasone for Patients With Multiple Myeloma

NCT00375791

COMPLETED Phase 2

Placebo-Controlled Study of Perifosine + Single Agent Chemotherapy for Metastatic Cancer Patients

NCT00398879

COMPLETED Phase 1

Phase I Trial of Paclitaxel With Perifosine

NCT00399126

COMPLETED Phase 1

Phase I Trial of Docetaxel With Perifosine

NCT00399087

COMPLETED Phase 1

A Phase 1/2 Trial of Perifosine in the Treatment of Non-Small Cell Lung Cancer

NCT00399789

COMPLETED Phase 1

Phase I Perifosine and Gemcitabine Study

NCT00398697

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 6
Phase 3 8

How the AEterna Zentaris early-phase archive is shaped

21 indexed studies, none listed as recruiting (0% open); 17 completed (81%).

Phase mix: 8 late (III/IV) vs 13 early (I/II) (early-phase heavy).

Top condition: Benign Prostatic Hypertrophy (1 trial), 3 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

AEterna Zentaris: archived-pipeline peers nationwide

Peers matched on 21 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

AEterna Zentaris sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0510152025 0%5%10%15%20% Total trials Recruiting share AEterna ZentarisAmphastar PharmaceuticalsApellis PharmaceuticalsArray Biopharma, now a wholly owned subsidiary of PfizerBasilea Pharmaceutica10xBio22nd Century Group23andMe3-C Institute for Social Development
AEterna Zentaris sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

AEterna Zentaris sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 21 archived trials

Sponsors with similar archive density (± trial count)

What to do with this AEterna Zentaris page

21 registered trials is a research-attention snapshot, not an endorsement of AEterna Zentaris or any single study.

  • None of AEterna Zentaris's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Benign Prostatic Hypertrophy is the condition AEterna Zentaris studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Benign Prostatic Hypertrophy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

AEterna Zentaris pipeline card: 21 registered trials from official public datasets.Report a data error.