Amphastar Pharmaceuticals

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Amphastar Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#714 of 15,742 sponsors by registered trial count).

21 total trials 1 currently recruiting 15 completed early-phase tilt top decile by trial count

Amphastar Pharmaceuticals: 21 sponsored US clinical trials, 1 recruiting.

Amphastar Pharmaceuticals sponsors 21 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 15 completed. 8 of these trials are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Asthma, with 4 trials.

Top-decile sponsor footprint

Amphastar Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#714 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 27/100

15 of 20 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (75.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

21 total, page 1 of 1

RECRUITING Phase 2

Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers

NCT07560150

COMPLETED Phase 2

Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar Rapid-Acting Insulin Aspart (I004) and NovoLog After Single-Dose Subcutaneous Administration to Healthy Volunteers

NCT05539872

COMPLETED Phase 4

Study of Drug Exposure in Systemic Circulation of Primatene Mist by Oral Inhalation, Versus Epinephrine Injection by Intramuscular Injection and ProAir by Oral Inhalation in Healthy Individuals

NCT04207840

COMPLETED Phase 2

Evaluation of Pharmacokinetics and Safety of A006 in Healthy Volunteers

NCT02271334

COMPLETED Phase 2

Albuterol DPI (A006) Clinical Study-B3:Efficacy, Dose-ranging and Safety Evaluation

NCT02210806

TERMINATED Phase 1

Assessment and Evaluation of Pharmacokinetic Profile of E004 in Healthy Adults

NCT01737892

COMPLETED Phase 3

Evaluation of Efficacy and Safety for Single Dose of E004 in Children With Asthma

NCT01737905

COMPLETED Phase 2

Evaluation of the Allergenicity of AMPHADASE INJECTION (Hyaluronidase Injection USP)

NCT01689363

COMPLETED Phase 2

Albuterol DPI (A006) Clinical Study-B2: Efficacy, Dose-Ranging and Initial Safety Evaluation

NCT01581177

COMPLETED Phase 3

Safety Study in Adolescent and Adult Patients With Asthma

NCT01476904

COMPLETED Phase 3

Evaluation of Efficacy and Safety of E004 in Children With Asthma

NCT01460511

COMPLETED Phase 3

Epinephrine Inhalation Aerosol USP: For Evaluation Of Efficacy And Safety In Asthma Patients

NCT01357642

COMPLETED Phase 2

Epinephrine Inhalation Aerosol USP, CLINICAL STUDY-B3 FOR ASSESSMENT OF PHARMACOKINETICS

NCT01255709

COMPLETED Phase 1

Epinephrine Inhalation Aerosol USP, a HFA-MDI Study for Assessment of Pharmacokinetics

NCT01188577

COMPLETED Phase 2

Dose-Ranging Study of A006 DPI, in Adult Asthma Patients

NCT01174732

COMPLETED Phase 2

Escalating and Cumulative-Dose Study of Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety of A006

NCT01189396

COMPLETED Phase 1

Pharmacokinetics (PK) Study of Epinephrine Inhalation Aerosol in Healthy Volunteers

NCT01143051

TERMINATED Phase 1

Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients.

NCT01025648

TERMINATED Phase 3

4-Week Study of Efficacy, Safety and PK of Albuterol-HFA Versus Proventil-HFA in Pediatric Asthma

NCT00634517

TERMINATED Phase 3

Single-Dose Cross-Over Study of the Effects of Albuterol-HFA in Exercise Induced Bronchoconstriction

NCT00634829

TERMINATED Phase 3

Controlled, 12-Week Study of Albuterol HFA Versus the Active Control, Proventil(R)-HFA in Asthmatic Patients

NCT00635505

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 9
Phase 3 7
Phase 4 1

What is open in the Amphastar Pharmaceuticals pipeline

1 recruiting of 21 indexed (5% open); 15 completed (71%).

Phase mix: 8 late (III/IV) vs 13 early (I/II) (early-phase heavy).

Top condition: Asthma (4 trials), 4 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Amphastar Pharmaceuticals: open-pipeline peers nationwide

Peers matched on 21 registered trials and 5% open enrollment, not the therapeutic-area sidebar.

Amphastar Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 20.920.92121.1 0%5%10%15%20% Total trials Recruiting share Amphastar PharmaceuticalsAEterna ZentarisApellis PharmaceuticalsArray Biopharma, now a wholly owned subsidiary of PfizerBasilea PharmaceuticaCook County HealthDavid Grant U.S. Air Force Medical CenterDuquesne UniversityLegacy Health System
Amphastar Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Amphastar Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 21 trials (± recruiting share)

Sponsors near 5% open enrollment (± trial volume)

What to do with this Amphastar Pharmaceuticals page

21 registered trials is a research-attention snapshot, not an endorsement of Amphastar Pharmaceuticals or any single study.

  • 1 of Amphastar Pharmaceuticals's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Asthma is the condition Amphastar Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Asthma trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Amphastar Pharmaceuticals pipeline card: 21 registered trials from official public datasets.Report a data error.