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NCT00415064 · ClinicalTrials.gov registry record · Phase 1

Phase I Study of Perifosine + Lenalidomide and Dexamethasone for Patients With Multiple Myeloma

A Phase 1 study of Multiple Myeloma, sponsored by AEterna Zentaris.

Completed
Registry status
Phase 1
Development phase
32
Enrollment target
1
Study location

NCT00415064 is a Phase 1 study of Multiple Myeloma that has completed, run by AEterna Zentaris. The registered enrollment target is 32 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00415064, a Phase 1 study of Multiple Myeloma, has completed, sponsored by AEterna Zentaris.

COMPLETED
Registry status
Phase 1
Development phase
32 participants
Enrollment target
1
Study location

Study Summary

This is a phase I study of perifosine in combination with lenalidomide and dexamethasone for patients with relapsed or refractory multiple myeloma. The current protocol will enroll patients with relapsed or refractory multiple myeloma requiring second or third line therapy. Six patients each will be treated with at one of 4 dose levels in a phase 1 study. All patients will receive perifosine, lenalidomide and dexamethasone of each 28 day cycle. The doses of perifosine and lenalidomide will be varied in each group. The dose of dexamethasone will remain constant.

Conditions Studied

Multiple Myeloma

Interventions

  • DRUG Dexamethasone
  • DRUG Lenalidomide
  • DRUG Perifosine

Study Locations (1)

Michigan

  • - Ann Arbor

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2006-12
Est. Completion 2012-07
Phase Phase 1

Sponsor

AEterna Zentaris

21 total trials

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What the Registry Record Tells You About NCT00415064

The ClinicalTrials.gov registry entry for NCT00415064 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (94% lower). The listed sponsor is AEterna Zentaris, which has 21 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 3 interventions - of which Dexamethasone is the first listed.

NCT00415064 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT00415064 about?

NCT00415064 is a clinical study titled "Phase I Study of Perifosine + Lenalidomide and Dexamethasone for Patients With Multiple Myeloma". This is a phase I study of perifosine in combination with lenalidomide and dexamethasone for patients with relapsed or refractory multiple myeloma. The current protocol will enroll patients with relapsed or refractory multiple myeloma requiring second or third line therapy. Six patients each will be...

What is the current status of trial NCT00415064?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2006-12. Estimated completion is 2012-07.

What conditions does trial NCT00415064 study?

This clinical trial studies the following conditions: Multiple Myeloma.

What interventions are being tested in trial NCT00415064?

The interventions under investigation include: Dexamethasone (DRUG), Lenalidomide (DRUG), Perifosine (DRUG).

Who is sponsoring clinical trial NCT00415064?

This trial is sponsored by AEterna Zentaris, which has 21 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00415064 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.