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NCT01224730 · ClinicalTrials.gov registry record · Phase 1

A Food Effect and QTc Study of Perifosine in Patients With Advanced Malignancies

A Phase 1 study of Cancer, sponsored by AEterna Zentaris.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target
2
Study locations

NCT01224730 is a Phase 1 study of Cancer that has completed, run by AEterna Zentaris. The registered enrollment target is 24 participants, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT01224730, a Phase 1 study of Cancer, has completed, sponsored by AEterna Zentaris.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target
2
Study locations

Study Summary

This is a Phase I study which will analyze any food-drug effects as well as QTc effects of perifosine. Safety and efficacy will also be evaluated. Patients who complete the first 24 days on single agent perifosine may have the opportunity to 1) continue on single agent perifosine; 2) switch to the combination of capecitabine + perifosine; or 3) switch to the combination of sorafenib + perifosine.

Conditions Studied

Interventions

  • DRUG perifosine

Study Locations (2)

Texas

  • - Dallas
  • - Houston

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2012-01-24
Est. Completion 2013-11-04
Phase Phase 1

Sponsor

AEterna Zentaris

21 total trials

What the Registry Record Tells You About NCT01224730

The ClinicalTrials.gov registry entry for NCT01224730 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (99% lower). The listed sponsor is AEterna Zentaris, which has 21 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cancer appearing as the primary indexed condition, and to 1 intervention - of which perifosine is the first listed.

NCT01224730 reports 2 study locations spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT01224730 about?

NCT01224730 is a clinical study titled "A Food Effect and QTc Study of Perifosine in Patients With Advanced Malignancies". This is a Phase I study which will analyze any food-drug effects as well as QTc effects of perifosine. Safety and efficacy will also be evaluated. Patients who complete the first 24 days on single agent perifosine may have the opportunity to 1) continue on single agent perifosine; 2) switch to the ...

What is the current status of trial NCT01224730?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2012-01-24. Estimated completion is 2013-11-04.

What conditions does trial NCT01224730 study?

This clinical trial studies the following conditions: Cancer.

What interventions are being tested in trial NCT01224730?

The interventions under investigation include: perifosine (DRUG).

Who is sponsoring clinical trial NCT01224730?

This trial is sponsored by AEterna Zentaris, which has 21 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01224730 being conducted?

This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.