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NCT05008835 · ClinicalTrials.gov registry record · Phase 2
Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee
A Phase 2 study, sponsored by ACADIA Pharmaceuticals.
- Terminated
- Registry status
- Phase 2
- Development phase
- 61
- Enrollment target
NCT05008835: Clinical Trial Phase 2 study, sponsored by ACADIA Pharmaceuticals.
NCT05008835 is a Phase 2 study that was terminated before completion, run by ACADIA Pharmaceuticals. The registered enrollment target is 61 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (54% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05008835, a Phase 2 study, was terminated before completion, sponsored by ACADIA Pharmaceuticals.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 61 participants
- Enrollment target
Study Summary
To evaluate the efficacy of ACP-044 compared with placebo in the treatment of pain associated with osteoarthritis of the knee
Primary Outcome
The 0-10 NRS consists of a single 11-point numeric scale, with 0 indicating no pain at all and 10 reflecting the worst pain imaginable. Due to the business decision to discontinue clinical development of ACP-044, this study was prematurely terminated. Efficacy was not evaluated in this study by using (planned) inferential statistics. For the purpose of results posting, changes in NRS over time are displayed using descriptive statistics.
Interventions
- DRUG Placebo
- DRUG ACP-044 Dose A
- DRUG ACP-044 Dose B
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2021-07-20 |
| Est. Completion | 2022-11-16 |
| Phase | Phase 2 |
Why NCT05008835 stopped before completion
NCT05008835 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (54% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT05008835 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05008835 about?
NCT05008835 is a clinical study titled "Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee". To evaluate the efficacy of ACP-044 compared with placebo in the treatment of pain associated with osteoarthritis of the knee
What is the current status of trial NCT05008835?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 61 participants. The study started on 2021-07-20. Estimated completion is 2022-11-16.
What interventions are being tested in trial NCT05008835?
The interventions under investigation include: Placebo (DRUG), ACP-044 Dose A (DRUG), ACP-044 Dose B (DRUG).
Who is sponsoring clinical trial NCT05008835?
This trial is sponsored by ACADIA Pharmaceuticals, which has 35 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05008835's enrollment target sits among peer trials
61 1026th of 2000 higher than 974 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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