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COMPLETED Phase 3

A Safety Study of Pimavanserin in Adult and Elderly Subjects Experiencing Neuropsychiatric Symptoms Related to Neurodegenerative Disease

NCT03575052 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess the safety and tolerability of pimavanserin compared to placebo in adult and elderly subjects with neuropsychiatric symptoms related to neurodegenerative disease.

Interventions

  • DRUG Placebo
  • DRUG Pimavanserin

Study Locations (20)

Florida

  • Indago Research & Health Center Inc — Hialeah
  • Reliable Clinical Research, LLC — Hialeah
  • Axcess Medical Research — Loxahatchee Groves
  • Premier Clinical Research Institute, Inc. — Miami
  • Global Medical Institutes — Miami
  • Future Care Solution, LLC — Miami
  • MediClear Medical & Research Center, Inc. — Miami
  • Novel Clinical Research LLC — Miami
  • Laszlo J Mate, MD, PA — North Palm Beach
  • University of South Florida — Tampa
  • Synexus Clinical Research US — The Villages

California

  • ATP Clinical Research, Inc. — Costa Mesa
  • Syrentis Clinical Research — Santa Ana

Arizona

  • Cognitive Clinical Trials — Gilbert

Massachusetts

  • Boston Center Memory — Newton

Nebraska

  • Cognitive Clinical Trials LLC — Papillion

New Jersey

  • The NeuroCognitive Institute — Mount Arlington

North Carolina

  • UNC Hospital — Chapel Hill

Ohio

  • Insight Clinical Trials LLC — Shaker Heights

Trial Details

FieldValue
Enrollment Target 784 participants
Start Date 2018-05-21
Est. Completion 2022-05-06
Phase Phase 3

Sponsor

ACADIA Pharmaceuticals

10 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03575052

The ClinicalTrials.gov registry entry for NCT03575052 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 784 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is ACADIA Pharmaceuticals, which has 10 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Neuropsychiatric Symptoms Related to Neurodegenerative Disease appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03575052 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Florida, California, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03575052 about?

NCT03575052 is a clinical study titled "A Safety Study of Pimavanserin in Adult and Elderly Subjects Experiencing Neuropsychiatric Symptoms Related to Neurodegenerative Disease". The purpose of this study is to assess the safety and tolerability of pimavanserin compared to placebo in adult and elderly subjects with neuropsychiatric symptoms related to neurodegenerative disease.

What is the current status of trial NCT03575052?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 784 participants. The study started on 2018-05-21. Estimated completion is 2022-05-06.

What conditions does trial NCT03575052 study?

This clinical trial studies the following conditions: Neuropsychiatric Symptoms Related to Neurodegenerative Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03575052?

The interventions under investigation include: Placebo (DRUG), Pimavanserin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03575052?

This trial is sponsored by ACADIA Pharmaceuticals, which has 10 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03575052 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Massachusetts, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial