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NCT01807572 · ClinicalTrials.gov registry record
Relation of Consummatory and Anticipatory Food Reward to Obesity
A clinical trial, sponsored by Oregon Research Institute.
- Completed
- Registry status
- 162
- Enrollment target
NCT01807572: Completed study, sponsored by Oregon Research Institute.
NCT01807572 is a clinical trial that has completed, run by Oregon Research Institute. The registered enrollment target is 162 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01807572 has completed, sponsored by Oregon Research Institute.
- COMPLETED
- Registry status
- 162 participants
- Enrollment target
Study Summary
Obesity is associated with increased risk for mortality, atherosclerotic cerebrovascular disease, coronary heart disease, colorectal cancer, hyperlipidemia, hypertension, gallbladder disease, and diabetes mellitus, resulting in over 111,000 deaths annually in the United States ). In the US, 65% of adults are overweight or obese. Unfortunately, the treatment of choice for obesity (behavioral weight loss treatment) only results in a 10% reduction in body weight on average and most patients regain this weight within a few years. Further, most obesity prevention programs do not reduce risk for future weight gain. The limited success of treatment and prevention interventions may be due to an incomplete understanding of the processes that increase risk for obesity. Recent data suggest that obese adults show abnormalities in reward from food intake and anticipated food intake relative to lean adults, but the precise nature of these abnormalities is unclear and it has not been established whether these abnormalities predate obesity onset or are a consequence. It is vital to elucidate risk factors for obesity onset to advance understanding of etiological processes and determine the content of prevention and treatment programs. The goals of this study are to (1) determine whether adolescents at high-risk for obesity, by virtue of having two obese parents, show abnormalities in reward from food intake (consummatory food reward) and anticipated reward from food intake (anticipatory food reward) compared to adolescents who are at low-risk for obesity, (2) determine whether abnormalities in consummatory and anticipatory food reward increase risk for weight gain and obesity onset, (3) examine moderators that may amplify the relations of consummatory and anticipatory food reward to unhealthy weight gain, and (4) examine changes in consummatory and anticipatory food reward in those participants who show obesity onset relative to those not showing obesity onset. Each of these goals
Primary Outcome
Using fMRI to test whether high-risk youth for obesity show differential neural responses in the striatum, and oral somatosensory and gustatory related brain regions when anticipating and during intake of a palatable food, relative to youth at low risk for obesity.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 162 participants |
| Start Date | 2009-06 |
| Est. Completion | 2015-07 |
What the finished NCT01807572 record still lists
NCT01807572 is an observational study that tracks outcomes without assigning an intervention. The registered 162 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01807572 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01807572 about?
NCT01807572 is a clinical study titled "Relation of Consummatory and Anticipatory Food Reward to Obesity". Obesity is associated with increased risk for mortality, atherosclerotic cerebrovascular disease, coronary heart disease, colorectal cancer, hyperlipidemia, hypertension, gallbladder disease, and diabetes mellitus, resulting in over 111,000 deaths annually in the United States ). In the US, 65% of a...
What is the current status of trial NCT01807572?
This trial is currently completed. The enrollment target is 162 participants. The study started on 2009-06. Estimated completion is 2015-07.
Who is sponsoring clinical trial NCT01807572?
This trial is sponsored by Oregon Research Institute, which has 62 total clinical trials registered on ClinicalTrials.gov.
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