Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03215888 · ClinicalTrials.gov registry record
Effects of Change in Insulin Resistance and Systemic Inflammation on Brain Structure and Function
A clinical trial, sponsored by University of Minnesota.
- Completed
- Registry status
- 29
- Enrollment target
NCT03215888: Completed study, sponsored by University of Minnesota.
NCT03215888 is a clinical trial that has completed, run by University of Minnesota. The registered enrollment target is 29 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03215888 has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- 29 participants
- Enrollment target
Study Summary
Obesity is associated with alterations in brain structure and cognitive impairment and is a risk factor for Alzheimer's disease and vascular dementia. The mechanisms underlying obesity related decline in cognitive function are not fully understood. The long-term goal of this project is to understand how obesity affects cognitive function, with the aim to develop new ways to prevent and treat obesity related cognitive decline
Primary Outcome
Change in insulin resistance and blood inflammatory markers from baseline (before surgery) and at 6 months post surgery
Interventions
- PROCEDURE bariatric surgery
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2017-11-01 |
| Est. Completion | 2020-02-11 |
What the finished NCT03215888 record still lists
NCT03215888 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 29 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which bariatric surgery is the first listed.
NCT03215888 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03215888 about?
NCT03215888 is a clinical study titled "Effects of Change in Insulin Resistance and Systemic Inflammation on Brain Structure and Function". Obesity is associated with alterations in brain structure and cognitive impairment and is a risk factor for Alzheimer's disease and vascular dementia. The mechanisms underlying obesity related decline in cognitive function are not fully understood. The long-term goal of this project is to understand...
What is the current status of trial NCT03215888?
This trial is currently completed. The enrollment target is 29 participants. The study started on 2017-11-01. Estimated completion is 2020-02-11.
What interventions are being tested in trial NCT03215888?
The interventions under investigation include: bariatric surgery (PROCEDURE).
Who is sponsoring clinical trial NCT03215888?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02429557 · 29 participants · Phase 1
Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure
- NCT02568878 · 29 participants · Phase 3
Creatine for Depressed Male and Female Methamphetamine Users
- NCT03014401 · 29 participants · NA
The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis
- NCT03128996 · 29 participants · Phase 1
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI