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NCT04275037 · ClinicalTrials.gov registry record · NA
The Hypotensive Effects of Home-Based Isometric Handgrip Training in Older Adults With Pre-Hypertension and Hypertension - The HoldAge Trial
A NA study, sponsored by University Institute of Maia.
- Completed
- Registry status
- NA
- Development phase
- 84
- Enrollment target
NCT04275037: Completed NA study, sponsored by University Institute of Maia.
NCT04275037 is a NA study that has completed, run by University Institute of Maia. The registered enrollment target is 84 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04275037, a NA study, has completed, sponsored by University Institute of Maia.
- COMPLETED
- Registry status
- NA
- Development phase
- 84 participants
- Enrollment target
Study Summary
New data suggests that isometric handgrip training (IHT) might become a novel tool in the treatment of hypertension. The main purpose of this research project is to evaluate the effects of home-based IHT on ambulatory blood pressure in older adults with pre-hypertension and hypertension. Eighty-four older adults with pre-hypertension and hypertension will be randomly distributed to one of three groups: home-based IHT, home-based aerobic exercise training (AET), or attention-control group (CON). Each intervention will have a total duration of 8 weeks. At baseline and after completing the intervention, patients will undergo the following evaluations: 24-hour ambulatory blood pressure, cardiorespiratory fitness, endothelial function, damage and repair, arterial stiffness, inflammatory biomarkers, autonomic function, physical activity levels, dietary intake and quality of life. A qualitative analysis will also be applied to enhance the understanding of the efficacy of this intervention from the patient's perspective.
Interventions
- OTHER Aerobic Exercise Training
- OTHER Isometric Handgrip Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2021-04-12 |
| Est. Completion | 2023-01-30 |
| Phase | NA |
What the finished NCT04275037 record still lists
NCT04275037 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which Aerobic Exercise Training is the first listed.
NCT04275037 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04275037 about?
NCT04275037 is a clinical study titled "The Hypotensive Effects of Home-Based Isometric Handgrip Training in Older Adults With Pre-Hypertension and Hypertension - The HoldAge Trial". New data suggests that isometric handgrip training (IHT) might become a novel tool in the treatment of hypertension. The main purpose of this research project is to evaluate the effects of home-based IHT on ambulatory blood pressure in older adults with pre-hypertension and hypertension. Eighty-four...
What is the current status of trial NCT04275037?
This trial is currently completed. It is a NA study. The enrollment target is 84 participants. The study started on 2021-04-12. Estimated completion is 2023-01-30.
What interventions are being tested in trial NCT04275037?
The interventions under investigation include: Aerobic Exercise Training (OTHER), Isometric Handgrip Training (OTHER).
Who is sponsoring clinical trial NCT04275037?
This trial is sponsored by University Institute of Maia, which has 1 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04275037's enrollment target sits among peer trials
84 983rd of 2000 higher than 1,011 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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