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NCT04327934 · ClinicalTrials.gov registry record · Early Phase 1
Mechanisms of Hypertension in Women With Polycystic Ovary Syndrome
A Early Phase 1 study, sponsored by Yale University.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 28
- Enrollment target
NCT04327934: Clinical Trial Early Phase 1 study, sponsored by Yale University.
NCT04327934 is a Early Phase 1 study that was terminated before completion, run by Yale University. The registered enrollment target is 28 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04327934, a Early Phase 1 study, was terminated before completion, sponsored by Yale University.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 28 participants
- Enrollment target
Study Summary
Women with androgen excess polycystic ovary syndrome (AE-PCOS) leads to hypertension.
Primary Outcome
forearm blood flow (ultrasound)/mean arterial pressure as a linear function of lower body negative pressure. This is an important measure of autonomic control of blood pressure. Indicating the the sensitivity of changes in vessel diameter in response to blood pooling (induced by lower body negative pressure).
Interventions
- DRUG GnRH antagonist
- DRUG GnRH antagonist + MethylTESTOSTERone 5 MG
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2017-12-01 |
| Est. Completion | 2022-06-30 |
| Phase | Early Phase 1 |
Why NCT04327934 stopped before completion
NCT04327934 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (47% lower).
The record links to 0 conditions, and to 2 interventions - of which GnRH antagonist is the first listed.
NCT04327934 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04327934 about?
NCT04327934 is a clinical study titled "Mechanisms of Hypertension in Women With Polycystic Ovary Syndrome". Women with androgen excess polycystic ovary syndrome (AE-PCOS) leads to hypertension.
What is the current status of trial NCT04327934?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 28 participants. The study started on 2017-12-01. Estimated completion is 2022-06-30.
What interventions are being tested in trial NCT04327934?
The interventions under investigation include: GnRH antagonist (DRUG), GnRH antagonist + MethylTESTOSTERone 5 MG (DRUG).
Who is sponsoring clinical trial NCT04327934?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04327934's enrollment target sits among peer trials
28 938th of 2000 higher than 1,038 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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