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Venous Leg Ulcer: later-stage trial registry
20 of 36 indexed Venous Leg Ulcer trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #419 of 28,707 conditions by registered trial count.
36 US clinical trials · 20 currently recruiting · #419 of 28,707 conditions by registered trial count
Venous Leg Ulcer: 36 US clinical trials tracked, 20 recruiting.
Venous Leg Ulcer is the subject of 36 registered US clinical trials on ClinicalTrials.gov, 20 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is BioLab Holdings, running 3 of these trials.
Enrollment posture brief
Registry condition venous-leg-ulcer
OPEN 20 | RECR 56% | LATE 8 | EARLY 5 | RANK #419 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Acute Lymphoblastic Leukemia, Pediatric (56% recruiting · 9 trials)
Venous Leg Ulcer lists 20 open slots (56% of 36 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Venous Leg Ulcer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Venous Leg Ulcer is recruiting above its size-band peers.
20 of 36 indexed trials (55.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Venous Leg Ulcer trials is spread across many organizations.
BioLab Holdings accounts for 3 of 36 trials (8.3%). 31 distinct sponsors appear on at least one study for this condition label.
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Typical Venous Leg Ulcer enrolment sits around 150 participants.
Median target enrolment is 150 among the 36 trials that report a genuine target (sentinel values excluded). 12 of those (33.3%) plan for fewer than 100 participants.
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Venous Leg Ulcer research is mostly interventional.
34 interventional and 2 observational studies make up this index (94.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
36 total, page 1 of 1
Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers
BioLab Holdings
NCT07089602
A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers
Integra LifeSciences Corporation
NCT06453187
Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.
Tiger Biosciences
NCT06826339
Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs
Stability Biologics
NCT06560502
Tissue Repair Gel in Venous Leg Ulcers in AU/US
TR Therapeutics
NCT06707103
Tissue Repair Gel in Venous Leg Ulcers (US)
TR Therapeutics
NCT06707090
Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating DFU and SanoGraft® in Treating VLU to SOC
Surgenex
NCT06515093
Real World Evidence with the Debritom+ TM Novel Micro Water Jet Technology At a Single Wound Center
Medaxis
NCT04920253
The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study
W.L.Gore & Associates
NCT05489588
CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations
Capsicure
NCT07046767
Human Amniotic Membrane On Venous Leg Ulcers In an Elderly Population
BioLab Holdings
NCT06544564
Evaluating the Durability of Closure for Venous Leg Ulcers
Kerecis
NCT06697925
INNOVEN: Efficacy of Porcine Placental Extracellular Matrix Plus Standard of Care (SOC) Versus SOC Alone
ConvaTec
NCT06606210
A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.
Molnlycke Health Care AB
NCT05588583
Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC
BioStem Technologies
NCT06811909
A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.
BioLab Holdings
NCT07364630
Dermacyte® Amniotic Wound Care Liquid for the Treatment of Non-Healing Venous Stasis Ulcers
Merakris Therapeutics
NCT04647240
Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy
Wake Forest University Health Sciences
NCT03716167
A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered Foam Dressing
Molnlycke Health Care AB
NCT05608317
Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Venous Leg Ulcers
NuScience Medical Biologics
NCT07061613
Geko™ Cross Therapy Registry - Wound
Firstkind
NCT05007301
Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers
Cellution Biologics
NCT06562296
Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Therapy-resistant CVU (Phase III)
RHEACELL GmbH & Co. KG
NCT06489028
Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial)
Washington University School of Medicine
NCT03250247
Developing Strategies for Effective Debridement in Patients for Venous Leg Ulcers
University of Miami
NCT03796793
The GORE® VIABAHN® FORTEGRA Venous Stent IVC Study
W.L.Gore & Associates
NCT05409976
Efficacy of TR 987, Beta-1,3-1,6-D-glucan, in the Treatment of Chronic Venous Insufficiency Ulcers
SerenaGroup
NCT03154619
Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers
Organogenesis
NCT00909870
Study to Evaluate Safety and Efficacy of GrafixPL for the Treatment of Venous Leg Ulcers
Osiris Therapeutics
NCT03629236
Intermittent Pneumatic Compression of the Thigh
Huntleigh Healthcare
NCT05659394
Dose-response Relationship Study of S42909 on Leg Ulcer Healing
Ilkos Therapeutic
NCT03077165
A Study to Evaluate the Safety and the Efficacy of EscharEx (EX-02 Formulation) in Debridement of Venous Leg Ulcers
MediWound
NCT03588130
Human Amniotic Membrane Grafting and Standard of Care Versus Standard of Care Alone in the Treatment of Venous Leg Ulcers
MiMedx Group
NCT01552447
Omeza Combination Therapy With Standard of Care to Standard of Care Alone for Chronic Venous Leg Ulcers
Omeza
NCT05291169
Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ulcers (VLUs)
Tactile Medical
NCT02395302
Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Venous Leg Ulcers
Xequel Bio
NCT02652572
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 4 |
| Phase 3 | 4 |
| Phase 4 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Venous Leg Ulcer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Venous Leg Ulcer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Venous Leg Ulcer page
36 registered trials, 20 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 20 Venous Leg Ulcer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- BioLab Holdings sponsors the most Venous Leg Ulcer trials on record, review their full trial history before evaluating a specific study. See BioLab Holdings's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Venous Leg Ulcer condition card totals 36 registered trials; most-linked intervention GORE® VIAFORT Vascular Stent; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.