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ClinicalTrials.gov 1 recruiting now official registry

Untreated Adult Acute Myeloid Leukemia clinical trials

1 of 13 indexed Untreated Adult Acute Myeloid Leukemia trials are currently recruiting.

13 US clinical trials · 1 currently recruiting

Untreated Adult Acute Myeloid Leukemia is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is Fred Hutchinson Cancer Center, running 3 of these trials.

The research picture

Untreated Adult Acute Myeloid Leukemia has 13 registered US clinical trials, 1 of them open to new participants right now, about 8% of the total.

1
recruiting participants now
8%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
3
top sponsor: Fred Hutchinson Cancer Center
Phase 15Phase 26

Active & Recent Trials

13 total, page 1 of 1

RECRUITING Phase 2 270 participants

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

M.D. Anderson Cancer Center

NCT00801489

ACTIVE NOT RECRUITING Phase 2 57 participants

Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patients

Wake Forest University Health Sciences

NCT02835222

ACTIVE NOT RECRUITING Phase 1 30 participants

Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia

City of Hope Medical Center

NCT03009240

COMPLETED Phase 2 546 participants

Decitabine as Maintenance Therapy After Standard Therapy in Treating Patients With Previously Untreated Acute Myeloid Leukemia

National Cancer Institute (NCI)

NCT00416598

COMPLETED Phase 1 199 participants

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Fred Hutchinson Cancer Center

NCT02044796

COMPLETED Phase 2 50 participants

Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative Neoplasm

University of Washington

NCT01101880

COMPLETED Phase 2 39 participants

Biomarkers in Predicting Treatment Response to Sirolimus and Chemotherapy in Patients With High-Risk Acute Myeloid Leukemia

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT02583893

COMPLETED Phase 1 39 participants

Bendamustine and Idarubicin in Treating Older Patients With Previously Untreated AML or MDS

Fred Hutchinson Cancer Center

NCT01141725

COMPLETED Phase 1 28 participants

Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS

Fred Hutchinson Cancer Center

NCT02921061

COMPLETED 14 participants

Metabolic Changes in Blood Samples From Patients With Acute Myeloid Leukemia

Wake Forest University Health Sciences

NCT02581917

COMPLETED Phase 1 13 participants

Pacritinib and Chemotherapy in Treating Patients With Acute Myeloid Leukemia and FLT3 Mutations

Bhavana Bhatnagar

NCT02323607

COMPLETED NA 12 participants

Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative Neoplasm

University of Washington

NCT02121418

COMPLETED Phase 2 12 participants

PXD101 in Treating Patients With Acute Myeloid Leukemia

National Cancer Institute (NCI)

NCT00357032

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Untreated Adult Acute Myeloid Leukemia Trial Landscape

13 indexed Untreated Adult Acute Myeloid Leukemia studies · 1 recruiting (8%).

Phase mix: 0 late (III/IV) vs 11 early (I/II).

Top sponsor: Fred Hutchinson Cancer Center (3 trials), 7 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Untreated Adult Acute Myeloid Leukemia?

PlainTrial tracks 13 US clinical trials for Untreated Adult Acute Myeloid Leukemia, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Untreated Adult Acute Myeloid Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.