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ClinicalTrials.gov 10 recruiting now official registry

Triple Negative Breast Cancer (TNBC) clinical trials

10 of 15 indexed Triple Negative Breast Cancer (TNBC) trials are currently recruiting.

15 US clinical trials · 10 currently recruiting

Triple Negative Breast Cancer (TNBC) is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Antonio Giordano, MD, running 1 of these trials.

The research picture

Triple Negative Breast Cancer (TNBC) has 15 registered US clinical trials, 10 of them open to new participants right now, about 67% of the total.

10
recruiting participants now
67%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
1
top sponsor: Antonio Giordano, MD
Phase 113Phase 22

Active & Recent Trials

15 total, page 1 of 1

RECRUITING Phase 1 396 participants

Study of XB010 in Subjects With Solid Tumors

Exelixis

NCT06545331

RECRUITING Phase 1 345 participants

A Study of NX-1607 in Adults With Advanced Malignancies

Nurix Therapeutics

NCT05107674

RECRUITING Phase 1 230 participants

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals

NCT05985655

RECRUITING Phase 1 205 participants

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

NiKang Therapeutics

NCT07029399

RECRUITING Phase 1 150 participants

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

Aktis Oncology

NCT07020117

RECRUITING Phase 1 150 participants

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

Normunity AccelCo

NCT07182149

RECRUITING Phase 1 102 participants

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

Jacobio Pharmaceuticals Co.

NCT05490472

RECRUITING Phase 1 80 participants

PQ203 in Advanced Malignant Tumors Including Triple Negative Breast Cancer

ProteinQure

NCT07190469

RECRUITING Phase 2 78 participants

PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease

UNC Lineberger Comprehensive Cancer Center

NCT07069595

RECRUITING Phase 1 20 participants

A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer

Calibr, a division of Scripps Research

NCT06878248

ACTIVE NOT RECRUITING Phase 1 150 participants

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

AbbVie

NCT03893955

ACTIVE NOT RECRUITING Phase 1 144 participants

A Study of ADRX-0706 in Select Advanced Solid Tumors

Adcentrx Therapeutics

NCT06036121

ACTIVE NOT RECRUITING Phase 1 85 participants

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Boundless Bio

NCT05827614

ACTIVE NOT RECRUITING Phase 1 50 participants

Onvansertib + Paclitaxel In TNBC

Antonio Giordano, MD

NCT05383196

ACTIVE NOT RECRUITING Phase 2 30 participants

OCTANE: Adjuvant Liposomal Doxorubicin and Carboplatin for Early-stage Triple-negative Breast Cancer

Mridula George, MD

NCT05949021

Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Triple Negative Breast Cancer (TNBC) Trial Landscape

15 indexed Triple Negative Breast Cancer (TNBC) studies · 10 recruiting (67%).

Phase mix: 0 late (III/IV) vs 15 early (I/II).

Top sponsor: Antonio Giordano, MD (1 trial), 9 others listed. 15 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Triple Negative Breast Cancer (TNBC)?

PlainTrial tracks 15 US clinical trials for Triple Negative Breast Cancer (TNBC), of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Triple Negative Breast Cancer (TNBC)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.