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Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors
NCT05985655 · View on ClinicalTrials.gov ↗
Study Summary
The primary purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK) and anti-tumor activity of GTAEXS617 (REC-617) in participants with advanced solid tumors.
Conditions Studied
Interventions
- DRUG GTAEXS617
- DRUG SoC
Study Locations (12)
Other
- GZA Ziekenhuizen - Campus Sint-Augustinus — Antwerp
- Clinique Universitaires Saint-Luc — Brussels
- Institute Jules Bordet — Brussels
- CHU Sart Tilman — Liège
- The Beatson West of Scotland Cancer Centre — Glasgow
- UCL Hospitals NHS Foundation Trust — London
- The Christie NHS Foundation Trust — Manchester
- Newcastle Upon Tyne NHS Foundation Trust — Newcastle upon Tyne
- Oxford University Hospitals NHS Foundation Trust — Oxford
Michigan
- START Midwest — Grand Rapids
Texas
- START San Antonio — San Antonio
Utah
- START Mountain Region — West Valley City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 230 participants |
| Start Date | 2023-07-06 |
| Est. Completion | 2028-05 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05985655
The ClinicalTrials.gov registry entry for NCT05985655 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 230 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 6 conditions, with Pancreatic Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions — of which GTAEXS617 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05985655 reports 12 study locations spanning 4 distinct geographic areas — top geographies include Other, Michigan, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05985655 about?
NCT05985655 is a clinical study titled "Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors". The primary purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK) and anti-tumor activity of GTAEXS617 (REC-617) in participants with advanced solid tumors.
What is the current status of trial NCT05985655?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 230 participants. The study started on 2023-07-06. Estimated completion is 2028-05.
What conditions does trial NCT05985655 study?
This clinical trial studies the following conditions: Pancreatic Adenocarcinoma, Non-small Cell Lung Cancer (NSCLC), Triple Negative Breast Cancer (TNBC), Head and Neck Squamous Cell Carcinoma (HNSCC), Platinum-resistant High-grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers (HGSOC). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05985655?
The interventions under investigation include: GTAEXS617 (DRUG), SoC (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05985655?
This trial is sponsored by Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05985655 being conducted?
This trial has 12 study locations across Michigan, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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