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NCT05985655 · ClinicalTrials.gov registry record · Phase 1

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

A Phase 1 study of Pancreatic Adenocarcinoma and Non-small Cell Lung Cancer (NSCLC), sponsored by Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals.

Recruiting
Registry status
Phase 1
Development phase
230
Enrollment target
12
Study locations

NCT05985655: Recruiting Phase 1 study of Pancreatic Adenocarcinoma and Non-small Cell Lung Cancer (NSCLC), sponsored by Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals.

NCT05985655 is a Phase 1 study of Pancreatic Adenocarcinoma and Non-small Cell Lung Cancer (NSCLC) that is actively recruiting participants, run by Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals. The registered enrollment target is 230 participants, below the 99,461-participant average among 62 other Pancreatic Adenocarcinoma trials with a reported enrollment target (100% lower). The trial reports 12 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05985655, a Phase 1 study of Pancreatic Adenocarcinoma and Non-small Cell Lung Cancer (NSCLC), is actively recruiting participants, sponsored by Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals.

RECRUITING
Registry status
Phase 1
Development phase
230 participants
Enrollment target
12
Study locations

Study Summary

The primary purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK) and anti-tumor activity of GTAEXS617 (REC-617) in participants with advanced solid tumors.

Interventions

  • DRUG GTAEXS617
  • DRUG SoC

Study Locations (12)

Other

  • GZA Ziekenhuizen - Campus Sint-Augustinus - Antwerp
  • Clinique Universitaires Saint-Luc - Brussels
  • Institute Jules Bordet - Brussels
  • CHU Sart Tilman - Liège
  • The Beatson West of Scotland Cancer Centre - Glasgow
  • UCL Hospitals NHS Foundation Trust - London
  • The Christie NHS Foundation Trust - Manchester
  • Newcastle Upon Tyne NHS Foundation Trust - Newcastle upon Tyne
  • Oxford University Hospitals NHS Foundation Trust - Oxford

Michigan

  • START Midwest - Grand Rapids

Texas

  • START San Antonio - San Antonio

Utah

  • START Mountain Region - West Valley City

Trial Details

FieldValue
Enrollment Target 230 participants
Start Date 2023-07-06
Est. Completion 2028-05
Phase Phase 1

What NCT05985655 shows while recruiting

NCT05985655 is an interventional study that assigns participants to a tested intervention. The registered 230 participants enrollment target is mid-sized for trials with a published cap, below the 99,461-participant average among 62 other Pancreatic Adenocarcinoma trials with a reported enrollment target (100% lower).

The record links to 6 conditions, with Pancreatic Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions - of which GTAEXS617 is the first listed.

NCT05985655 lists 12 locations in 4 states (Other, Michigan, Texas).

Frequently Asked Questions

What is clinical trial NCT05985655 about?

NCT05985655 is a clinical study titled "Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors". The primary purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK) and anti-tumor activity of GTAEXS617 (REC-617) in participants with advanced solid tumors.

What is the current status of trial NCT05985655?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 230 participants. The study started on 2023-07-06. Estimated completion is 2028-05.

What conditions does trial NCT05985655 study?

This clinical trial studies the following conditions: Pancreatic Adenocarcinoma, Non-small Cell Lung Cancer (NSCLC), Triple Negative Breast Cancer (TNBC), Head and Neck Squamous Cell Carcinoma (HNSCC), Platinum-resistant High-grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers (HGSOC).

What interventions are being tested in trial NCT05985655?

The interventions under investigation include: GTAEXS617 (DRUG), SoC (DRUG).

Who is sponsoring clinical trial NCT05985655?

This trial is sponsored by Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05985655 being conducted?

This trial has 12 study locations across Michigan, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pancreatic Adenocarcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05985655's enrollment target sits among peer trials

230 16th of 62 higher than 47 of 62 other Pancreatic Adenocarcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pancreatic Adenocarcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05985655, the US trial registry maintained by the National Library of Medicine. NCT05985655 (mid enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.