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ClinicalTrials.gov 3 recruiting now official registry

Tenosynovial Giant Cell Tumor clinical trials

3 of 9 indexed Tenosynovial Giant Cell Tumor trials are currently recruiting.

9 US clinical trials · 3 currently recruiting

Tenosynovial Giant Cell Tumor is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Deciphera Pharmaceuticals, running 3 of these trials.

The research picture

Tenosynovial Giant Cell Tumor has 9 registered US clinical trials, 3 of them open to new participants right now, about 33% of the total.

3
recruiting participants now
33%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
3
top sponsor: Deciphera Pharmaceuticals
Phase 13Phase 21Phase 33

Active & Recent Trials

9 total, page 1 of 1

RECRUITING Phase 1 276 participants

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in Patients With Advanced Solid Tumor

Abbisko Therapeutics Co

NCT04192344

RECRUITING 100 participants

Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With Vimseltinib

Deciphera Pharmaceuticals

NCT07075471

RECRUITING 30 participants

A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment

Daiichi Sankyo

NCT04635111

ACTIVE NOT RECRUITING Phase 3 123 participants

Study of Vimseltinib for Tenosynovial Giant Cell Tumor

Deciphera Pharmaceuticals

NCT05059262

ACTIVE NOT RECRUITING Phase 1 120 participants

Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor

Deciphera Pharmaceuticals

NCT03069469

ACTIVE NOT RECRUITING Phase 3 90 participants

Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)

Abbisko Therapeutics Co

NCT05804045

COMPLETED Phase 3 120 participants

Phase 3 Study of Pexidartinib for Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCT-TS)

Daiichi Sankyo

NCT02371369

COMPLETED Phase 1 66 participants

Study of Cabiralizumab in Patients With Pigmented Villonodular Synovitis / Diffuse Type Tenosynovial Giant Cell Tumor

Five Prime Therapeutics

NCT02471716

COMPLETED Phase 2 17 participants

Nilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell Tumor

Andrew J. Wagner, MD, PhD

NCT01207492

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 1
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Tenosynovial Giant Cell Tumor Trial Landscape

9 indexed Tenosynovial Giant Cell Tumor studies · 3 recruiting (33%).

Phase mix: 3 late (III/IV) vs 4 early (I/II).

Top sponsor: Deciphera Pharmaceuticals (3 trials), 4 others listed. 9 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Tenosynovial Giant Cell Tumor?

PlainTrial tracks 9 US clinical trials for Tenosynovial Giant Cell Tumor, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Tenosynovial Giant Cell Tumor?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.