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2026 data Public-data reference. official source

Stage IV Cutaneous Melanoma AJCC v6 and v7

Open-data reference.

18 US clinical trials ·

Active & Recent Trials

ACTIVE NOT RECRUITING Phase 3 1,673 participants

Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery

National Cancer Institute (NCI)

NCT01274338

ACTIVE NOT RECRUITING Phase 2 600 participants

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

National Cancer Institute (NCI)

NCT02339571

ACTIVE NOT RECRUITING Phase 2 280 participants

Testing Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has Spread

National Cancer Institute (NCI)

NCT02196181

ACTIVE NOT RECRUITING Phase 2 245 participants

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

National Cancer Institute (NCI)

NCT01134614

ACTIVE NOT RECRUITING Phase 2 88 participants

Ipilimumab With or Without High-Dose Recombinant Interferon Alfa-2b in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

National Cancer Institute (NCI)

NCT01708941

ACTIVE NOT RECRUITING Phase 2 72 participants

Dinaciclib in Treating Patients With Stage IV Melanoma

National Cancer Institute (NCI)

NCT00937937

ACTIVE NOT RECRUITING Phase 1 70 participants

Aerosolized Aldesleukin in Treating Patients With Lung Metastases

M.D. Anderson Cancer Center

NCT01590069

ACTIVE NOT RECRUITING Phase 1 62 participants

Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors, Melanoma, Prostate or Kidney Cancer

National Cancer Institute (NCI)

NCT01480154

ACTIVE NOT RECRUITING Phase 2 52 participants

Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma

M.D. Anderson Cancer Center

NCT02910700

ACTIVE NOT RECRUITING Phase 2 43 participants

Talimogene Laherparepvec and Pembrolizumab in Treating Patients With Stage III-IV Melanoma

National Cancer Institute (NCI)

NCT02965716

ACTIVE NOT RECRUITING Phase 1 35 participants

Riluzole and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors or Melanoma

National Cancer Institute (NCI)

NCT01303341

ACTIVE NOT RECRUITING Phase 1 34 participants

Genetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV Melanoma

M.D. Anderson Cancer Center

NCT01955460

ACTIVE NOT RECRUITING Phase 1 20 participants

Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Mayo Clinic

NCT03021460

ACTIVE NOT RECRUITING Phase 1 19 participants

Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies

National Cancer Institute (NCI)

NCT01364051

ACTIVE NOT RECRUITING Phase 2 18 participants

Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma

National Cancer Institute (NCI)

NCT02581930

COMPLETED Phase 2 169 participants

Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

National Cancer Institute (NCI)

NCT01950390

COMPLETED Phase 2 18 participants

Pembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic Melanoma

M.D. Anderson Cancer Center

NCT02500576

COMPLETED Phase 2 11 participants

Tumor-Infiltrating Lymphocytes After Combination Chemotherapy in Treating Patients With Metastatic Melanoma

Fred Hutchinson Cancer Center

NCT01807182

Phase Distribution

PhaseTrial count
Early Phase 1 6
Phase 2 11
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Stage IV Cutaneous Melanoma AJCC v6 and v7 Trial Landscape

ClinicalTrials.gov lists 18 US studies indexed under Stage IV Cutaneous Melanoma AJCC v6 and v7, and 0 of those are currently open to recruitment — roughly 0% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Stage IV Cutaneous Melanoma AJCC v6 and v7 shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 17 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Stage IV Cutaneous Melanoma AJCC v6 and v7 is led by National Cancer Institute (NCI) with 12 indexed trials, alongside 3 other organizations in the top contributor list. The list on this page surfaces up to 18 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Stage IV Cutaneous Melanoma AJCC v6 and v7?

PlainTrial tracks 18 US clinical trials for Stage IV Cutaneous Melanoma AJCC v6 and v7, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stage IV Cutaneous Melanoma AJCC v6 and v7?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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