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ClinicalTrials.gov 1 recruiting now early-phase tilt small index

Stage IIB Breast Cancer: early-phase trial registry

1 of 15 indexed Stage IIB Breast Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 1 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Stage IIB Breast Cancer: 15 US clinical trials tracked, 1 recruiting.

Stage IIB Breast Cancer is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is City of Hope Medical Center, running 3 of these trials.

Enrollment posture brief

Registry condition stage-iib-breast-cancer

OPEN 1 | RECR 7% | LATE 3 | EARLY 6 | RANK #1140 | SPON 3

Nearest open-share peer: Liver Disease (7% recruiting · 15 trials)

Advanced Lung Non-Small Cell53.3%AIDS26.7%Stage IIB Breast Cancer (thi…7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Stage IIB Breast Cancer

Stage IIB Breast Cancer lists 1 open slots (7% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stage IIB Breast Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stage IIB Breast Cancer is recruiting below its size-band peers.

    1 of 15 indexed trials (6.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Stage IIB Breast Cancer research.

    City of Hope Medical Center accounts for 3 of 15 trials (20%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Most Stage IIB Breast Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 63 among the 15 trials that report a genuine target (sentinel values excluded). 10 of those (66.7%) plan for fewer than 100 participants.

  4. Stage IIB Breast Cancer research is mostly interventional.

    13 interventional and 2 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 26Phase 33

Open and recent trials

15 total, page 1 of 1

RECRUITING Phase 2 88 participants

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

Jonsson Comprehensive Cancer Center

NCT04553770

ACTIVE NOT RECRUITING Phase 3 898 participants

Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

Alliance for Clinical Trials in Oncology

NCT03414970

ACTIVE NOT RECRUITING Phase 3 782 participants

Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

NRG Oncology

NCT02488967

ACTIVE NOT RECRUITING Phase 3 415 participants

Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

ECOG-ACRIN Cancer Research Group

NCT02445391

ACTIVE NOT RECRUITING Phase 2 108 participants

Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction

Ohio State University Comprehensive Cancer Center

NCT02927912

ACTIVE NOT RECRUITING Phase 2 67 participants

Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Locally Advanced or Inflammatory Triple Negative Breast Cancer

City of Hope Medical Center

NCT01525966

ACTIVE NOT RECRUITING Phase 2 63 participants

Pertuzumab, Trastuzumab, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With HER2-Positive Advanced Breast Cancer

City of Hope Medical Center

NCT01730833

ACTIVE NOT RECRUITING Phase 2 62 participants

Pegylated Liposomal Doxorubicin Hydrochloride and Carboplatin Followed by Surgery and Paclitaxel in Treating Patients With Triple Negative Stage II-III Breast Cancer

Rutgers, The State University of New Jersey

NCT02315196

ACTIVE NOT RECRUITING Phase 2 46 participants

Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Ca

Virginia Commonwealth University

NCT02957968

COMPLETED 178 participants

Functional Magnetic Resonance Imaging in Assessing Affect Reactivity and Regulation in Patients With Stage 0-III Breast Cancer

Stanford University

NCT03050463

COMPLETED NA 50 participants

Exercise Intervention in Preventing Breast Cancer Recurrence in Postmenopausal Breast Cancer Survivors

City of Hope Medical Center

NCT02235051

COMPLETED 33 participants

MRI and Cardio-Pulmonary Exercise Testing in Evaluating Exercise Intolerance in Patients With Stage I-III Breast Cancer After Chemotherapy Treatment

Wake Forest University Health Sciences

NCT02702830

COMPLETED NA 28 participants

FLT PET in Measuring Treatment Response in Patients With Newly Diagnosed Estrogen Receptor-Positive, HER2-Negative Stage I-III Breast Cancer

University of Washington

NCT01928186

COMPLETED NA 15 participants

Computerized Cognitive Retraining in Improving Cognitive Function in Breast Cancer Survivors

Fred Hutchinson Cancer Center

NCT02662335

COMPLETED NA 4 participants

Aerobic and Strength Training Exercise in Improving Fitness and Arm Health During and After Radiation Therapy in Patients With Stage II-III Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT03102866

Phase Distribution

PhaseTrial count
Phase 2 6
Phase 3 3

Named interventions

Most-linked intervention names on Stage IIB Breast Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
5 trials
laboratory biomarker analysis Other
3 trials
Laboratory Biomarker Analysis Other
3 trials
Quality-of-Life Assessment Other
3 trials
Carboplatin Drug
3 trials
paclitaxel albumin-stabilized nanoparticle formulation Drug
2 trials
carboplatin Drug
2 trials
Radiation Therapy Radiation
2 trials

US sites by state

Facility locations filed on Stage IIB Breast Cancer trials. A trial with sites in several states counts in each.

California 7 trials
Ohio 3 trials
Arizona 3 trials
Alaska 3 trials
Washington 2 trials
North Carolina 2 trials
Arkansas 2 trials
Alabama 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stage IIB Breast Cancer page

15 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage IIB Breast Cancer condition card totals 15 registered trials; most-linked intervention Questionnaire Administration; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.