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ClinicalTrials.gov enrollment closed early-phase tilt small index

Stage IA Breast Cancer: early-phase trial registry

A small indexed set (14 trials) with no open enrollment listed right now.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · none currently recruiting · #1,230 of 28,707 conditions by registered trial count

Stage IA Breast Cancer: 14 US clinical trials tracked, none currently recruiting.

Stage IA Breast Cancer is the subject of 14 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Wake Forest University Health Sciences, running 2 of these trials.

Enrollment posture brief

Registry condition stage-ia-breast-cancer

OPEN 0 | RECR 0% | LATE 1 | EARLY 4 | RANK #1230 | SPON 2

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)

Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%Stage IA Breast Cancer (this)0%
Open-enrollment share among volume-matched conditions near Stage IA Breast Cancer

Stage IA Breast Cancer has no open enrollment in this registry pull (14 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stage IA Breast Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stage IA Breast Cancer is recruiting below its size-band peers.

    0 of 14 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Stage IA Breast Cancer trials is spread across many organizations.

    Wake Forest University Health Sciences accounts for 2 of 14 trials (14.3%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Typical Stage IA Breast Cancer enrolment sits around 108 participants.

    Median target enrolment is 108 among the 14 trials that report a genuine target (sentinel values excluded). 7 of those (50%) plan for fewer than 100 participants.

  4. Stage IA Breast Cancer research is mostly interventional.

    12 interventional and 2 observational studies make up this index (85.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 24Phase 31

Indexed trials (enrollment closed)

14 total, page 1 of 1

ACTIVE NOT RECRUITING NA 1,259 participants

Intraoperative Radiation Therapy in Treating Patients With Breast Cancer Undergoing Breast-Conserving Surgery

University of California, San Francisco

NCT01570998

ACTIVE NOT RECRUITING NA 1,046 participants

A Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS)

ECOG-ACRIN Cancer Research Group

NCT01824836

ACTIVE NOT RECRUITING Phase 2 108 participants

Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction

Ohio State University Comprehensive Cancer Center

NCT02927912

ACTIVE NOT RECRUITING Phase 2 92 participants

Paclitaxel & Cyclophosphamide With or Without Trastuzumab Before Surgery in Treating Previously Untreated Breast Cancer

University of Nebraska

NCT01750073

COMPLETED Phase 3 280 participants

Combination Chemotherapy and Paclitaxel Plus Trastuzumab in Treating Women With Palpable Breast Cancer That Can Be Removed by Surgery

National Cancer Institute (NCI)

NCT00513292

COMPLETED Phase 2 200 participants

Accelerated Partial Breast Radiation Therapy Using High-Dose Rate Brachytherapy in Treating Patients With Early Stage Breast Cancer After Surgery

Rutgers, The State University of New Jersey

NCT02526498

COMPLETED 178 participants

Functional Magnetic Resonance Imaging in Assessing Affect Reactivity and Regulation in Patients With Stage 0-III Breast Cancer

Stanford University

NCT03050463

COMPLETED NA 144 participants

Diindolylmethane in Treating Patients With Breast Cancer

University of Arizona

NCT01391689

COMPLETED NA 71 participants

Brief Behavioral Therapy in Improving Sleep Disorders in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy

Gary Morrow

NCT02002533

COMPLETED Phase 2 57 participants

Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast Cancer

Wake Forest University Health Sciences

NCT01869764

COMPLETED NA 50 participants

Exercise Intervention in Preventing Breast Cancer Recurrence in Postmenopausal Breast Cancer Survivors

City of Hope Medical Center

NCT02235051

COMPLETED 33 participants

MRI and Cardio-Pulmonary Exercise Testing in Evaluating Exercise Intolerance in Patients With Stage I-III Breast Cancer After Chemotherapy Treatment

Wake Forest University Health Sciences

NCT02702830

COMPLETED NA 28 participants

FLT PET in Measuring Treatment Response in Patients With Newly Diagnosed Estrogen Receptor-Positive, HER2-Negative Stage I-III Breast Cancer

University of Washington

NCT01928186

COMPLETED NA 15 participants

Computerized Cognitive Retraining in Improving Cognitive Function in Breast Cancer Survivors

Fred Hutchinson Cancer Center

NCT02662335

Phase Distribution

PhaseTrial count
Phase 2 4
Phase 3 1

Named interventions

Most-linked intervention names on Stage IA Breast Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
4 trials
Laboratory Biomarker Analysis Other
4 trials
Radiation Therapy Radiation
2 trials
Paclitaxel Drug
2 trials
laboratory biomarker analysis Other
2 trials
Cyclophosphamide Drug
2 trials
Standard Follow-Up Care Procedure
1 trials
diindolylmethane Dietary supplement
1 trials

US sites by state

Facility locations filed on Stage IA Breast Cancer trials. A trial with sites in several states counts in each.

California 6 trials
North Carolina 4 trials
New York 3 trials
Illinois 3 trials
Washington 2 trials
Ohio 2 trials
New Jersey 2 trials
Michigan 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stage IA Breast Cancer page

14 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage IA Breast Cancer condition card totals 14 registered trials; most-linked intervention Questionnaire Administration; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.