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ClinicalTrials.gov 5 recruiting now full pipeline small index

Stage I Breast Cancer: full-pipeline trial registry

5 of 12 indexed Stage I Breast Cancer trials are currently recruiting.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 5 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Stage I Breast Cancer: 12 US clinical trials tracked, 5 recruiting.

Stage I Breast Cancer is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition stage-i-breast-cancer

OPEN 5 | RECR 42% | LATE 2 | EARLY 3 | RANK #1429 | SPON 3

Nearest open-share peer: Adiposity (42% recruiting · 12 trials)

Stage I Breast Cancer (this)42%Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Stage I Breast Cancer

Stage I Breast Cancer lists 5 open slots (42% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stage I Breast Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stage I Breast Cancer is recruiting below its size-band peers.

    5 of 12 indexed trials (41.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Stage I Breast Cancer research.

    Memorial Sloan Kettering Cancer Center accounts for 3 of 12 trials (25%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most Stage I Breast Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 12 trials that report a genuine target (sentinel values excluded). 8 of those (66.7%) plan for fewer than 100 participants.

  4. Stage I Breast Cancer research is mostly interventional.

    12 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 22Phase 31Phase 41

Open and recent trials

12 total, page 1 of 1

RECRUITING Phase 3 1,670 participants

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

NRG Oncology

NCT04852887

RECRUITING NA 270 participants

TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

Dana-Farber Cancer Institute

NCT05535192

RECRUITING NA 110 participants

Improving Exercise Capacity With a Tailored Physical Activity Intervention

Wake Forest University Health Sciences

NCT05595577

RECRUITING Phase 4 60 participants

A Study of Revaree Plus in People With Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT07042581

RECRUITING NA 30 participants

A Study of Disappearing Markers for Daily Radiation Treatment Delivery for Breast Cancer Patients.

Barbara Ann Karmanos Cancer Institute

NCT07095114

ACTIVE NOT RECRUITING NA 134 participants

Single Fraction Accelerated Partial Breast Irradiation vs. Five Fraction Accelerated Partial Breast Irradiation for Low-risk Stage 0 and I Breast Carcinoma

Washington University School of Medicine

NCT04849871

ACTIVE NOT RECRUITING Phase 2 62 participants

Niraparib + Dostarlimab In BRCA Mutated Breast Cancer

Dana-Farber Cancer Institute

NCT04584255

ACTIVE NOT RECRUITING Phase 2 48 participants

Acupuncture Pilot Study for Cancer-related Cognitive Function

Memorial Sloan Kettering Cancer Center

NCT04007770

ACTIVE NOT RECRUITING NA 33 participants

Researching the Effect of Exercise on Cancer

Memorial Sloan Kettering Cancer Center

NCT04589468

COMPLETED NA 55 participants

Cytoxan, Epirubicin and Capecitabine in Women With Breast Cancer

Craig A. Bunnell, MD, MPH

NCT00146588

COMPLETED Phase 1 40 participants

Defined Green Tea Catechin Extract in Treating Women With Hormone Receptor Negative Stage I-III Breast Cancer

National Cancer Institute (NCI)

NCT00516243

COMPLETED NA 17 participants

Living Well After Breast Surgery

University of Texas at Austin

NCT03834532

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 2
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Stage I Breast Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Educational website Other
1 trials
Breast reconstruction decision aid Other
1 trials
defined green tea catechin extract Drug
1 trials
questionnaire administration Procedure
1 trials
laboratory biomarker analysis Procedure
1 trials
External Beam Accelerated Partial Breast Irradiation Radiation
1 trials
16 week waiting period + optional Acupuncture Other
1 trials
Epirubicin Drug
1 trials

US sites by state

Facility locations filed on Stage I Breast Cancer trials. A trial with sites in several states counts in each.

New York 4 trials
New Jersey 3 trials
Massachusetts 3 trials
Texas 2 trials
California 2 trials
Washington 1 trials
Virginia 1 trials
Tennessee 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stage I Breast Cancer page

12 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage I Breast Cancer condition card totals 12 registered trials; most-linked intervention Educational website; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.