Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Scoliosis clinical trials
Every US clinical trial registered for Scoliosis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
18 US clinical trials · 11 currently recruiting
The research picture
Scoliosis has 18 registered US clinical trials, 11 of them open to new participants right now — about 61% of the total.
- 11
- recruiting participants now
- 61%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 4
- top sponsor: International Spine Study Group Foundation
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Clinical Orthopaedic Data Bank (Acute and Chronic)
University of Florida
NCT00411060
Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain
SpineZone Medical Fitness
NCT04081896
Complex Adult Deformity Surgery (CADS)
International Spine Study Group Foundation
NCT04194138
Prospective Multicenter Evaluation of a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis
St. Justine's Hospital
NCT02434003
Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery
International Spine Study Group Foundation
NCT04885244
Yoga for Back Pain in Adolescent Scoliosis
Johns Hopkins University
NCT06242821
Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients
International Spine Study Group Foundation
NCT04888104
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
Alcyone Therapeutics
NCT05866419
Virtual Reality's Effect on Decreasing Pain and Subsequent Opioid Use in Pediatric Patients in the Post-Operative Period Following Scoliosis Repair
Northwell Health
NCT05888038
Effect of Adult Spinal Deformity Surgery on Functional Reach
University of Kansas Medical Center
NCT06258161
Scoliosis Shared Decision Making
Mayo Clinic
NCT03107533
Postoperative and Chronic Pain Genetic Spine Surgery Study
Children's Hospital Medical Center, Cincinnati
NCT02998138
A Multicenter Prospective Study of Quality of Life in Adult Scoliosis
Washington University School of Medicine
NCT00854828
Min Implants Max Outcomes Clinical Trial
University of Minnesota
NCT01792609
Prospective Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity
International Spine Study Group Foundation
NCT01588054
Transfusion Requirements During Spinal Surgery for Severe Scoliosis
Rutgers, The State University of New Jersey
NCT01490164
Gait and Postural Stability Assessment in Children With Idiopathic Scoliosis Undergoing Posterior Spine Instrumentation
Shriners Hospitals for Children
NCT01109082
IRB-HSR# 14145 R,S Methadone: Analgesia and Pharmacokinetics in Adolescents Undergoing Scoliosis Correction
University of Virginia
NCT01205256
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Scoliosis Trial Landscape
ClinicalTrials.gov lists 18 US studies indexed under Scoliosis, and 11 of those are currently open to recruitment — roughly 61% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Scoliosis shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Scoliosis is led by International Spine Study Group Foundation with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 18 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Scoliosis?
PlainTrial tracks 18 US clinical trials for Scoliosis, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Scoliosis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.