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ClinicalTrials.gov 11 recruiting now later-stage tilt small index

Scoliosis: later-stage trial registry

11 of 18 indexed Scoliosis trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #953 of 28,707 conditions by registered trial count.

18 US clinical trials · 11 currently recruiting · #953 of 28,707 conditions by registered trial count

Scoliosis: 18 US clinical trials tracked, 11 recruiting.

Scoliosis is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is International Spine Study Group Foundation, running 4 of these trials.

Enrollment posture brief

Registry condition scoliosis

OPEN 11 | RECR 61% | LATE 1 | EARLY 0 | RANK #953 | SPON 4

Nearest open-share peer: Breast Cancer Metastatic (61% recruiting · 18 trials)

Scoliosis (this)61%Arrhythmias, Cardiac27.8%Androgenetic Alopecia16.7%Anemia, Sickle Cell16.7%Acquired Immunodeficiency Sy5.6%
Open-enrollment share among volume-matched conditions near Scoliosis

Scoliosis lists 11 open slots (61% of 18 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Scoliosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Scoliosis is recruiting above its size-band peers.

    11 of 18 indexed trials (61.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Scoliosis research.

    International Spine Study Group Foundation accounts for 4 of 18 trials (22.2%). 15 distinct sponsors appear on at least one study for this condition label.

  3. Typical Scoliosis enrolment sits around 225 participants.

    Median target enrolment is 225 among the 18 trials that report a genuine target (sentinel values excluded). 7 of those (38.9%) plan for fewer than 100 participants.

  4. Scoliosis research leans observational.

    6 interventional and 12 observational studies make up this index (33.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 31

Open and recent trials

18 total, page 1 of 1

RECRUITING 10,000 participants

Clinical Orthopaedic Data Bank (Acute and Chronic)

University of Florida

NCT00411060

RECRUITING 5,000 participants

Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain

SpineZone Medical Fitness

NCT04081896

RECRUITING 1,500 participants

Complex Adult Deformity Surgery (CADS)

International Spine Study Group Foundation

NCT04194138

RECRUITING 1,200 participants

Prospective Multicenter Evaluation of a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis

St. Justine's Hospital

NCT02434003

RECRUITING 500 participants

Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

International Spine Study Group Foundation

NCT04885244

RECRUITING NA 500 participants

Yoga for Back Pain in Adolescent Scoliosis

Johns Hopkins University

NCT06242821

RECRUITING 225 participants

Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients

International Spine Study Group Foundation

NCT04888104

RECRUITING NA 90 participants

Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

Alcyone Therapeutics

NCT05866419

RECRUITING NA 50 participants

Virtual Reality's Effect on Decreasing Pain and Subsequent Opioid Use in Pediatric Patients in the Post-Operative Period Following Scoliosis Repair

Northwell Health

NCT05888038

RECRUITING 30 participants

Effect of Adult Spinal Deformity Surgery on Functional Reach

University of Kansas Medical Center

NCT06258161

RECRUITING 25 participants

Scoliosis Shared Decision Making

Mayo Clinic

NCT03107533

ACTIVE NOT RECRUITING 880 participants

Postoperative and Chronic Pain Genetic Spine Surgery Study

Children's Hospital Medical Center, Cincinnati

NCT02998138

COMPLETED NA 286 participants

A Multicenter Prospective Study of Quality of Life in Adult Scoliosis

Washington University School of Medicine

NCT00854828

COMPLETED NA 200 participants

Min Implants Max Outcomes Clinical Trial

University of Minnesota

NCT01792609

COMPLETED 100 participants

Prospective Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity

International Spine Study Group Foundation

NCT01588054

COMPLETED 50 participants

Transfusion Requirements During Spinal Surgery for Severe Scoliosis

Rutgers, The State University of New Jersey

NCT01490164

COMPLETED 42 participants

Gait and Postural Stability Assessment in Children With Idiopathic Scoliosis Undergoing Posterior Spine Instrumentation

Shriners Hospitals for Children

NCT01109082

COMPLETED Phase 3 11 participants

IRB-HSR# 14145 R,S Methadone: Analgesia and Pharmacokinetics in Adolescents Undergoing Scoliosis Correction

University of Virginia

NCT01205256

Phase Distribution

PhaseTrial count
Phase 3 1

Named interventions

Most-linked intervention names on Scoliosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Index or spine revision surgery for complex adult spinal deformity Procedure
2 trials
Minimum Number of Screws Procedure
1 trials
Maximum Number of Screws Procedure
1 trials
Non-operative intervention Other
1 trials
posterior spine fusion Procedure
1 trials
virtual reality Device
1 trials
methadone Drug
1 trials
Video recording of clinical visit Other
1 trials

US sites by state

Facility locations filed on Scoliosis trials. A trial with sites in several states counts in each.

New York 8 trials
California 8 trials
Virginia 6 trials
Maryland 5 trials
Texas 4 trials
North Carolina 4 trials
Illinois 4 trials
Florida 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Scoliosis page

18 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Scoliosis condition card totals 18 registered trials; most-linked intervention Index or spine revision surgery for complex adult spinal deformity; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.