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ClinicalTrials.gov 11 recruiting now official registry

Scoliosis clinical trials

Every US clinical trial registered for Scoliosis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

18 US clinical trials · 11 currently recruiting

The research picture

Scoliosis has 18 registered US clinical trials, 11 of them open to new participants right now — about 61% of the total.

11
recruiting participants now
61%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
4
top sponsor: International Spine Study Group Foundation

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 10,000 participants

Clinical Orthopaedic Data Bank (Acute and Chronic)

University of Florida

NCT00411060

RECRUITING 5,000 participants

Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain

SpineZone Medical Fitness

NCT04081896

RECRUITING 1,500 participants

Complex Adult Deformity Surgery (CADS)

International Spine Study Group Foundation

NCT04194138

RECRUITING 1,200 participants

Prospective Multicenter Evaluation of a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis

St. Justine's Hospital

NCT02434003

RECRUITING 500 participants

Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

International Spine Study Group Foundation

NCT04885244

RECRUITING NA 500 participants

Yoga for Back Pain in Adolescent Scoliosis

Johns Hopkins University

NCT06242821

RECRUITING 225 participants

Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients

International Spine Study Group Foundation

NCT04888104

RECRUITING NA 90 participants

Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

Alcyone Therapeutics

NCT05866419

RECRUITING NA 50 participants

Virtual Reality's Effect on Decreasing Pain and Subsequent Opioid Use in Pediatric Patients in the Post-Operative Period Following Scoliosis Repair

Northwell Health

NCT05888038

RECRUITING 30 participants

Effect of Adult Spinal Deformity Surgery on Functional Reach

University of Kansas Medical Center

NCT06258161

RECRUITING 25 participants

Scoliosis Shared Decision Making

Mayo Clinic

NCT03107533

ACTIVE NOT RECRUITING 880 participants

Postoperative and Chronic Pain Genetic Spine Surgery Study

Children's Hospital Medical Center, Cincinnati

NCT02998138

COMPLETED NA 286 participants

A Multicenter Prospective Study of Quality of Life in Adult Scoliosis

Washington University School of Medicine

NCT00854828

COMPLETED NA 200 participants

Min Implants Max Outcomes Clinical Trial

University of Minnesota

NCT01792609

COMPLETED 100 participants

Prospective Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity

International Spine Study Group Foundation

NCT01588054

COMPLETED 50 participants

Transfusion Requirements During Spinal Surgery for Severe Scoliosis

Rutgers, The State University of New Jersey

NCT01490164

COMPLETED 42 participants

Gait and Postural Stability Assessment in Children With Idiopathic Scoliosis Undergoing Posterior Spine Instrumentation

Shriners Hospitals for Children

NCT01109082

COMPLETED Phase 3 11 participants

IRB-HSR# 14145 R,S Methadone: Analgesia and Pharmacokinetics in Adolescents Undergoing Scoliosis Correction

University of Virginia

NCT01205256

Phase Distribution

PhaseTrial count
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Scoliosis Trial Landscape

ClinicalTrials.gov lists 18 US studies indexed under Scoliosis, and 11 of those are currently open to recruitment — roughly 61% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Scoliosis shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Scoliosis is led by International Spine Study Group Foundation with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 18 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Scoliosis?

PlainTrial tracks 18 US clinical trials for Scoliosis, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Scoliosis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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