Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Risk Reduction

Open-data reference.

14 US clinical trials · 2 currently recruiting

Active & Recent Trials

RECRUITING 2,300 participants

Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

San Raffaele University

NCT05732623

RECRUITING Phase 4 150 participants

Blood Donor CVD 5000

University of Maryland, Baltimore

NCT03971669

ACTIVE NOT RECRUITING NA 1,200 participants

Tennessee Youth Prepared for Success

Centerstone Research Institute

NCT06001892

ACTIVE NOT RECRUITING Phase 2 120 participants

Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens

University of Kansas Medical Center

NCT04821141

COMPLETED NA 43,225 participants

Efficacy of Communication Modalities for Promoting Flu Shots

Geisinger Clinic

NCT05509270

COMPLETED NA 233 participants

Building Stronger Allies

Florida State University

NCT03571750

COMPLETED NA 196 participants

Prevention and Risk: Treatment With a New Emphasis on Relationships

Hunter College of City University of New York

NCT03396367

COMPLETED NA 148 participants

Acceptability, Feasibility, and Preliminary Impact of a Web-based, HIV Prevention Toolkit With Cisgender Male Couples in Lima, Peru

Florida International University

NCT05873855

COMPLETED NA 134 participants

Nature and Health: How Does Lifestyle and Environment Affect Health and Wellness

Stanford University

NCT06001697

COMPLETED NA 105 participants

Electronic Confirmed Versus Conventional Consenting Process: A Randomized Controlled Trial

The University of Texas Medical Branch, Galveston

NCT03510260

COMPLETED Phase 1 96 participants

Salmonella Conjugates CVD 1000: Study of Responses to Vaccination With Trivalent Invasive Salmonella Disease Vaccine

University of Maryland, Baltimore

NCT03981952

COMPLETED NA 80 participants

Rural Chronic Disease Risk Reduction

Florida State University

NCT05611580

COMPLETED NA 63 participants

PrEP Point-of-Care Brief-Intervention for Adherence Among Young Men Who Have Sex With Men

University of California, San Francis

NCT05353283

COMPLETED NA 30 participants

Monitoring Environmental Exposures and Behavioral Change

University of Utah

NCT05338242

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 2 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Risk Reduction Trial Landscape

ClinicalTrials.gov lists 14 US studies indexed under Risk Reduction, and 2 of those are currently open to recruitment — roughly 14% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Risk Reduction shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Risk Reduction is led by Florida State University with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 14 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Risk Reduction?

PlainTrial tracks 14 US clinical trials for Risk Reduction, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Risk Reduction?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →